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© 1993 Oxford University Press

review-article

Detection of the carcinogen 2-amino-1-methyl-6-phenyl-imidazo[4,5-b]pyridine (PhIP) in beer and wine

Shigeo Manabe, Hiramitsu Suzuki 1, Osamu Wada and Akira Ueki 2

Department of Hygiene and Preventive Medicine, Faculty of Medicine, University of Tokyo 7-3-1 Hongo, Bunkyo-ku, Tokyo 113
1National Food Research Institute 2-1-2 Kannondai, Yatabe, Tsukuba, Ibaraki 305
2Jichi Medical School Ohmiya Medical Center 1–847 Amanuma, Ohmiya 330, Japan

A carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), was measured in beer and wine by HPLC. PhIP was found to be present in all brands of beer and wine analyzed. The concentrations of PhIP in beer and wine were 14.1 ± 6.18 ng/l (mean ± SD, n = 11) and 30.4 ± 16.4 ng/l (n = 10) respectively.


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