Carcinogenesis, Vol. 25, No. 7, 1077-1081,
July 2004
Carcinogenesis vol.25 no.7 © Oxford University Press 2004; all rights reserved.
Anthony Dipple Carcinogenesis Award: COMMENTARY |
p53 from pathway to therapy
Department of Surgery and Molecular Oncology, Ninewells Hospital, University of Dundee, Dundee DD1 9SY, UK
Email: d.p.lane{at}dundee.ac.uk
Abstract
In the 25 years since its first description the p53 protein has been shown to play a key role in both tumour suppression and aging. New discoveries about the function and control of p53 continue to emerge every month and attempts to exploit the system to develop better therapeutics and diagnostics are beginning to be successful in the clinic (1,2).
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