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© 1985 Oxford University Press

research-article

Data on the carcinogenicity of chemicals in the IARC Monographs programme

H. Vainio , K. Hemminki 1 and J. Wilbourn 

International Agency for Research on Cancer 150 cours Albert Thomas, F-69372 Lyon Cedex 08, France
1Institute of Occupational Health Haartmaninkatu 1, SF-00290 Helsinki 29, Finland

Data were extracted from IARC Monographs volumes 1–38 on chemicals and exposures for which some data on carcinogenicity in humans, or sufficient evidence of carcinogenicity in experimental animals existed. In all, 288 chemicals, industrial processes and complex mixtures fulfilled these criteria. For 30 chemicals or mixtures of chemicals, and nine industrial processes, there was sufficient evidence of carcinogenicity in humans; and for 63 chemicals and mixtures of chemicals and for five industrial processes, there was evidence that these exposures were probably carcinogenic to humans. For 61 chemicals or groups of chemicals and six industrial processes or occupations, no evaluation of carcinogenicity to humans could be made. For 115 chemicals there is sufficient evidence of carcinogenicity to experimental animals, but no epidemiological data are available. Publications not earlier referred to on the carcinogenicity of these chemicals and exposures were found for ~70. A call is made for further information on these exposures with a view to updating the IARC Monographs.


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