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Carcinogenesis, Vol. 23, No. 4, 667-668, April 2002
© 2002 Oxford University Press


RESPONSE TO LETTER TO THE EDITOR

Association of CYP2C9 genotypes leading to high enzyme activity and colorectal cancer risk

Carmen Martínez1, Elena García-Martín2, José M. Ladero3, Javier Sastre4, Francisco Garcia-Gamito5, Manuel Diaz-Rubio3 and José A.G. Agúndez1,,6

1 Department of Pharmacology, Medical School and
2 Department of Biochemistry, School of Biological Sciences, University of Extremadura, Avda. de Elvas s/n. E-06071, Badajoz, Spain,
3 Service of Gastroenterology and
4 Medical Oncology, San Carlos University Hospital, Prof. Martin Lagos s/n, E-28040, Madrid, Spain and
5 Service of Surgery, Hospital INSALUD, Pol Nueva Ciudad s/n E-06800 Mérida, Spain

Dear Sir,

Thank you for the opportunity to reply the letter from Yasar et al. In their letter, Yasar et al., expressed concerns regarding the selection of the control group in our previous study (1). With regard to the first matter addressed i.e., that patients with benign diseases of the colon are more adequate controls than healthy subjects we do not agree for the following reasons.

From a clinical point of view it has little sense to compare cancer patients with patients with benign diseases. . . . [Full Text of this Article]

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References


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