Erratum
for Chang et al., Carcinogenesis 24 (11) 1749-1758.
Carcinogenesis, Vol. 25, No. 3, 463,
March 2004
Carcinogenesis vol.25 no.3 © Oxford University Press 2004; all rights reserved.
Osteopontin induction is required for tumor promoter-induced transformation of preneoplastic mouse cells
Pi-Ling Chang,
Minhton Cao and
Patricia Hicks
In the above article, part of the legend to Figure 5 was inadvertantly omitted. The figure and complete legend are reprinted below.
View larger version (33K):
[in this window]
[in a new window]
|
Fig. 5. RGD peptides do not inhibit OPN-induced JB6 cell transformation, however, antibody to OPN significantly reduces OPN-induced colony formation. (A) Cells were pre-incubated with GRGDSP (competitive) or GRGESP (negative control) peptides at 1 or 10 mM for 20 min prior to seeding on top of the 0.5% solidified agar layer with or without 45 µg/ml of OPN and incubated for 14 days. **P< 0.01 significantly different from respective controls, which do not have OPN (designated as OP or P) added. (B) OPN were pre-incubated with molar equivalent of purified anti-OPN or control IgG for 30 min prior to mixing with cells and layered on top of the 0.5% solidified agar. Negative control such as cells incubated with PBS, anti-OPN or IgG were also included. Histogram was plotted as the percent of colony formation relative to OPN-treated cells. The number of clones for the negative controls was in the range of 60 to 35 clones/10 000 cells. *P<0.05 significantly different OPN (OP)-treated cells.
|
|
CiteULike 
Connotea 
Del.icio.us What's this?
