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Carcinogenesis Advance Access originally published online on January 12, 2008
Carcinogenesis 2008 29(5):1083; doi:10.1093/carcin/bgm305
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© The Author 2008. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

‘Environment’ in cancer causation and etiological fraction: limitations and ambiguities

Dario Mirabelli* and Enzo Merler2

Unit of Cancer Epidemiology, CeRMS and CPO-Piemonte, University of Turin, Turin, Italy
2 Occupational Health Unit, Department of Prevention, Local Health Authority of Padua, Padua, Italy

* To whom correspondence should be addressed. Tel: +39 011 6336966; Fax: +39 011 6336960 Email: d.mirabelli@cpo.it

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Boffetta et al. (1) discussed in depth ‘the main "errors" that produce over-estimates’ in the attributable fraction of environmental cancer, because they are ‘less widely appreciated’ than those producing the opposite effect. We would like to focus on the risk of mesothelioma following environmental exposures to asbestos, the first environmental carcinogen taken into account by the authors in their paper and in a previous article (2), because we think that, on the contrary, it has often been overlooked.

A . . . [Full Text of this Article]


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