Carcinogenesis

COMMENTARY:

Werner K. Lutz

Dose-response relationship and low dose extrapolatioin in chemical carcinogenesis
Carcinogenesis 1990 11: 1243-1247; doi:10.1093/carcin/11.8.1243 [Abstract] [PDF] [Request Permissions]  

ORIGINAL ARTICLES:

S. Törnquist, L. Möller, J. Gabrielsson, J.-Å. Gustafsson, and R. Toftgård

2-Nitrofluorene metabolism in rat lung. Pharmacokinetic and metabolic effects of ß-naphthoflavone treatment
Carcinogenesis 1990 11: 1249-1254; doi:10.1093/carcin/11.8.1249 [Abstract] [PDF] [Request Permissions]  

Jan Erik Paulsen

Effects of retinoic acid on epiderma DNA synthesis induced by 12-O-tetradecanoylphorbol-13-acetate, mezerein or ethylphenylpropiolate in hairless mice
Carcinogenesis 1990 11: 1255-1258; doi:10.1093/carcin/11.8.1255 [Abstract] [PDF] [Request Permissions]  

Ole Vang, Marianne B. Jensen, and Herman Autrup

Induction of cytochrome P450IA1 in rat colon and liver by indole-3-carbinol and 5,6-benzoflavone
Carcinogenesis 1990 11: 1259-1263; doi:10.1093/carcin/11.8.1259 [Abstract] [PDF] [Request Permissions]  

Deborah R. Jaffe, Daniel Haraf, Jeffrey L. Schwartz, Ralph R. Weichselbaum, and Alan M. Diamond

Radioresistant derivatives of an X-ray-senstive CHO cell line exhibit distinct patterns of sensitivity to DNA-damaging agents
Carcinogenesis 1990 11: 1265-1269; doi:10.1093/carcin/11.8.1265 [Abstract] [PDF] [Request Permissions]  

Suresh H. Moolgavkar, E.Georg Luebeck, Mathisca de Gunst, Ruediger E. Port, and Michael Schwarz

Quantitative analysis of enzyme-altered foci in rat hepatocarcinogenesis experiments—I. Single agent regimen
Carcinogenesis 1990 11: 1271-1278; doi:10.1093/carcin/11.8.1271 [Abstract] [PDF] [Request Permissions]  

N. Fedtke, J.A. Boucheron, M. J. Turner, Jr, and J. A. Swenberg

Vinyl chloride-induced DNA adducts I: Quantitative determination of N²,3-ethenoguanine based on electrophore labeling
Carcinogenesis 1990 11: 1279-1285; doi:10.1093/carcin/11.8.1279 [Abstract] [PDF] [Request Permissions]  

N. Fedtke, J.A. Boucheron, V.E. Walker, and J.A. Swenberg

Vinyl chloride-induced DNA adducts II: Formating and persistence of 7-(2'oxoethyl)guanine and N² ,3 ethenoguanine in rat tissue DNA
Carcinogenesis 1990 11: 1287-1292; doi:10.1093/carcin/11.8.1287 [Abstract] [PDF] [Request Permissions]  

Charles L. Crespi, Bruce W. Penman, Julian A.E. Leakey, Michael P. Arlotto, Avishay Stark, Andrew Parkinson, Thomas Turner, Dorothy T. Steimel, Ken Rudo, Robin L. Davies, and Robert Langenbach

Human cytochrome P450IIA3: cDNA sequence role of the enzyme in the metabolic of promutagens comparison to nitrosamine activation by human cytochrome P450IIE1
Carcinogenesis 1990 11: 1293-1300; doi:10.1093/carcin/11.8.1293 [Abstract] [PDF] [Request Permissions]  

Floyd R. Fullerton, Karen Hoover, Yves B. Mikol, Donald A. Creasia, and Lionel A. Poirier

The inhibition by methionine and choline of liver carcinoma formation in male C3H mice dosed with diethylnitrosamine and fed phenobarbital
Carcinogenesis 1990 11: 1301-1305; doi:10.1093/carcin/11.8.1301 [Abstract] [PDF] [Request Permissions]  

M. Peluso, M. Castegnaro, C. Malaveille, G. Talaska, P. Vineis, F. Kadlubar, and H. Bartsch

³²P-Postlabelling analysis of DNA adducted with urinary mutagens from smokers of black tobacco
Carcinogenesis 1990 11: 1307-1311; doi:10.1093/carcin/11.8.1307 [Abstract] [PDF] [Request Permissions]  

Wolfgang Schmahl, Arne Luz, Maria Leierseder-Bauer, and Angelika Neuhäuser-Klaus

Diaplacental induction by ethylnitrosourea of tumours at the pial border of the central nervous system in (T x HT)F1 mice
Carcinogenesis 1990 11: 1313-1322; doi:10.1093/carcin/11.8.1313 [Abstract] [PDF] [Request Permissions]  

Shunji Kitazawa, Ayumi Denda, Masahiro Tsutsumi, Toshifumi Tsujiuchi, Kiyohiko Hasegawa, Kazutoshi Tamura, Hiroshi Maruyama, and Yoichi Konishi

Enhanced preneoplastic liver lesion development under ‘selection pressure’ conditions after administration of deoxycholic or lithocholic acid in the initiation phase in rats
Carcinogenesis 1990 11: 1323-1328; doi:10.1093/carcin/11.8.1323 [Abstract] [PDF] [Request Permissions]  

Lisa A. Peterson, Steven G. Carmella, and Stephen S. Hecht

Investigations of metabolic precursors to hemoglobin and DNA adducts of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
Carcinogenesis 1990 11: 1329-1333; doi:10.1093/carcin/11.8.1329 [Abstract] [PDF] [Request Permissions]  

Charles D. Hébert, Qun-Li Cao, and Linda S. Birnbaum

Inhibition of high-density growth arrest in human squamous carcinoma cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
Carcinogenesis 1990 11: 1335-1342; doi:10.1093/carcin/11.8.1335 [Abstract] [PDF] [Request Permissions]  

Miriam C. Poirier, Nancy F. Fullerton, Elroy D. Patterson, and Frederick A. Beland

DNA adduct formation and removal in hepatic chromatin fractions from rats chronically fed 2-acetylaminofluorene
Carcinogenesis 1990 11: 1343-1347; doi:10.1093/carcin/11.8.1343 [Abstract] [PDF] [Request Permissions]  

M.Vijayaraj Reddy, William T. Bleicher, Gary R. Blackburn, and Carl R. Mackerer

DNA adduction by phenol, hydroquinone, or benzoquinone in vitro but not in vivo: nuclease P1-enhanced ³²P-postlabeling of adducts as labeled nucleoside bisphosphates, dinucleotides and nucleoside monophosphates
Carcinogenesis 1990 11: 1349-1357; doi:10.1093/carcin/11.8.1349 [Abstract] [PDF] [Request Permissions]  

P. Cikryt, M. Göttlicher, and H.-G. Neumann

Competitive binding affinity of carcinogenic aromatic amines to the rat hepatic aromatic hydrocarbon (Ah) receptor in vitro and potency to induce monooxygenase activity in vivo
Carcinogenesis 1990 11: 1359-1366; doi:10.1093/carcin/11.8.1359 [Abstract] [PDF] [Request Permissions]  

Lee-Jane W. Lu and Mian-Ying Wang

Modulation of benzo[a]pyrene-induced covalent DNA modifications in adult and fetal mouse tissues by gestation stage
Carcinogenesis 1990 11: 1367-1372; doi:10.1093/carcin/11.8.1367 [Abstract] [PDF] [Request Permissions]  

P.J. Packer, B. Van Acker, P.I. Reed, K. Haines, M.H. Thompson, M.J. Hill, and S.A. Leach

The effect of gastric achlorhydria on the urinary recovery of nitrate in man: relevance to urinary nitrate as a measure of dietary nitrate exposure
Carcinogenesis 1990 11: 1373-1376; doi:10.1093/carcin/11.8.1373 [Abstract] [PDF] [Request Permissions]  

Fritz Klimek and Peter Bannasch

Biochemical microanalysis of pyruvate kinase activity in preneoplastic and neoplastic liver lesions induced in rats by N-nitrosomorpholine
Carcinogenesis 1990 11: 1377-1380; doi:10.1093/carcin/11.8.1377 [Abstract] [PDF] [Request Permissions]  

Takemi Kinouchi, Keiko Nishifuji, and Yoshinari Ohnishi

Biliary excretion of glutathione conjugates of 4,5-expoxy-4,5-dihydro-1-nitropyrene and 9,10-epoxy-9,10-dihydro-1-nitropyrene in rats administered 1-nitropyrene orally and their further metabolism in the intestinal tract
Carcinogenesis 1990 11: 1381-1387; doi:10.1093/carcin/11.8.1381 [Abstract] [PDF] [Request Permissions]  

Pertti Koivisto and Kari Hemminki

³²P-Postlabelling of 2-hydroxyethylated, ethylated and methytated adducts of 2'-deoxyguanosine 3'-monophosphate
Carcinogenesis 1990 11: 1389-1392; doi:10.1093/carcin/11.8.1389 [Abstract] [PDF] [Request Permissions]  

Richard H. Bell, Jr, Vincent A. Memoli, and Daniel S. Longnecker

Hyperplasia and tumors of the islets of Langerhans in mice bearing an elastase I-SV40) T-antigen fusion gene
Carcinogenesis 1990 11: 1393-1398; doi:10.1093/carcin/11.8.1393 [Abstract] [PDF] [Request Permissions]  

Lennart Romert, Jan Magnusson, and Claes Ramel

The importance of glutathione and glutathione transferase for somatic mutations in Drosophila melanogaster induced in vivo by 1,2-dichloroethane
Carcinogenesis 1990 11: 1399-1402; doi:10.1093/carcin/11.8.1399 [Abstract] [PDF] [Request Permissions]  

Takuji Tanaka, Yoshio Mori, Yukio Morishita, Akira Hara, Takatoshi Ohno, Toshihiro Kojima, and Hideki Mori

Inhibitory effect of sinigrin and indole-3-carbinol on diethytnitrosamine-induced hepatocarcinogenesis in male ACI/N rats
Carcinogenesis 1990 11: 1403-1406; doi:10.1093/carcin/11.8.1403 [Abstract] [PDF] [Request Permissions]  

Alan Cahill and Ian N.H. White

Reductive metabolism of 3-amino-1,2,4-benzotriazine-1,4-dioxide (SR 4233) and the induction of unscheduled DNA synthesis in rat and human derived cell lines
Carcinogenesis 1990 11: 1407-1411; doi:10.1093/carcin/11.8.1407 [Abstract] [PDF] [Request Permissions]  

Sten Flodström, Helean Hemming, Lars Wärngard, and Ulf G.Ahlborg

Promotion of altered hepatic foci development in rat liver, cytochrome P450 enzyme induction and inhibition of cell-cell communication by DDT and some structurally related organohalogen pesticides
Carcinogenesis 1990 11: 1413-1417; doi:10.1093/carcin/11.8.1413 [Abstract] [PDF] [Request Permissions]  

A.A. Wani, G. Wani, and S.M.D' Ambrosio

A human DNA repair activity specific for O⁴-ethylthymine: identification and partial characterization
Carcinogenesis 1990 11: 1419-1424; doi:10.1093/carcin/11.8.1419 [Abstract] [PDF] [Request Permissions]  

Setsuo Takai, M.Price Floyd, Katherine K. Sanford, Robert E. Tarone, and Ram Parshad

Persistence of chromatid damage after G₂ phase X-irradiation in lymphoblastoid cells from Gardner's syndrome
Carcinogenesis 1990 11: 1425-1428; doi:10.1093/carcin/11.8.1425 [Abstract] [PDF] [Request Permissions]  

SHORT COMMUNICATIONS:

P. Principe, G.D. Wilson, P.A. Riley, and T.F. Slater

In vitro transformation induces abnormal protein thiol levels in rat liver cells
Carcinogenesis 1990 11: 1429-1432; doi:10.1093/carcin/11.8.1429 [Abstract] [PDF] [Request Permissions]  

Patricia Servais, Gérard Taton, and Paul Galand

Modulation by indomethacin of diethylnitrosamine-induced early changes in c-myc and c-ras expression and late incidence of preneoplastic lesions in rat liver
Carcinogenesis 1990 11: 1433-1436; doi:10.1093/carcin/11.8.1433 [Abstract] [PDF] [Request Permissions]  

Luisa Airoldi, Cinzia Magagnotti, Marina Bonfanti, and Roberto Fanelli

Alpha-oxidative metabolism of the bladder carcinogens N-nitrosobutyl(4-hydroxybutyl)amine and N-nitrosobutyl(3-carboxypropyl)amine within the rat isolated bladder
Carcinogenesis 1990 11: 1437-1440; doi:10.1093/carcin/11.8.1437 [Abstract] [PDF] [Request Permissions]  

Jian-Hua Shen, Martin Wegenke, and Thomas Wolff

Capability of human blood cells to form the DNA adduct, C8-(N-aminofluorenyl)-deoxyguanosine-3'-5'-diphosphate from 2-aminofluorene
Carcinogenesis 1990 11: 1441-1444; doi:10.1093/carcin/11.8.1441 [Abstract] [PDF] [Request Permissions]  

Announcement:

Announcement
Carcinogenesis 1990 11: 1445; doi:10.1093/carcin/11.8.1445 [PDF] [Request Permissions]  

Author index:

Author index
Carcinogenesis 1990 11: 1446; doi:10.1093/carcin/11.8.1446 [PDF] [Request Permissions]  

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