Carcinogenesis

ORIGINAL ARTICLES:

Eric von Hofe, Ivo Schmerold, Raymond W. Nims, Larry K. Keefer, Elmer J. Reist, and Paul Kleihues

ß-Deuteration of N-nitrosoethylmethylamine causes a shift in DNA methylation from rat liver to esophagus
Carcinogenesis 1991 12: 545-549; doi:10.1093/carcin/12.4.545 [Abstract] [PDF] [Request Permissions]  

Kim M. Borges, John S. Boswell, Robert H. Liebross, and Karen E. Wetterhahn

Activation of chromium(VI) by thiols results in chromium(V) formation, chromium binding to DNA and altered DNA conformation
Carcinogenesis 1991 12: 551-561; doi:10.1093/carcin/12.4.551 [Abstract] [PDF] [Request Permissions]  

Irma Gimenez-Conti, Aurora Viaje, Judith Chesner, Claudio Conti, and Thomas J. Slaga

Induction of short-term markers of tumor promotion by organic peroxides
Carcinogenesis 1991 12: 563-569; doi:10.1093/carcin/12.4.563 [Abstract] [PDF] [Request Permissions]  

Eric J. Hunt and Ronald C. Shank

Formation and persistence of a DNA adduct in rodents treated with N-nitrosopyrrolidine
Carcinogenesis 1991 12: 571-575; doi:10.1093/carcin/12.4.571 [Abstract] [PDF] [Request Permissions]  

Ajit K. Roy, Pramod Upadhyaya, Prederick E. Evans, and karam El-Bayoumy

Structural characterization of the major adducts formed by reaction of 4,5-epoxy-4,5-dihydro-1-nitropyrene with DNA
Carcinogenesis 1991 12: 577-581; doi:10.1093/carcin/12.4.577 [Abstract] [PDF] [Request Permissions]  

Johannes Bax, Caria Schippers-Gillissen, Ruud A. Woutersen, and Ewalt Scherer

Cell specific DNA alkylation in traget and non-target organs of N-nitrosobis(2-oxopropyl)amine-induced carcinogenesis in hamster and rat
Carcinogenesis 1991 12: 583-590; doi:10.1093/carcin/12.4.583 [Abstract] [PDF] [Request Permissions]  

Eino Hietanen, Helmut Bartsch, Markku Ahotupa, Jean-Claude Béréziat, Valeria Bussacchini-Griot, Jose Ricardo Cabral, Anne-Marie Camus, Matti Laitinen, and Heather Wild

Mechanisms of fat-related modulation of N-nitrosodiethylamine-induced tumors in rats: organ distribution, blood lipids, enzymes and pro-oxidant state
Carcinogenesis 1991 12: 591-600; doi:10.1093/carcin/12.4.591 [Abstract] [PDF] [Request Permissions]  

Abulkalam M. Shamsuddin, Asad Ullah, Abdul Baten, and Eric Hale

Stability of fecapentaene-12 and its carcinogenicity in F-344 rats
Carcinogenesis 1991 12: 601-607; doi:10.1093/carcin/12.4.601 [Abstract] [PDF] [Request Permissions]  

Peter P. Fu, Dwight W. Miller, Linda S. Von Tungeln, Matthew S. Bryant, Jackson O. Lay, Jr, Kurt Huang, Lawanda Jones, and Frederick E. Evans

Formation of C8-modified deoxyguanosine and C8-modified deoxyadenosine as major DNA adducts from 2-nitropyrene metabolism mediated by rat and mouse liver microsomes and cytosols
Carcinogenesis 1991 12: 609-616; doi:10.1093/carcin/12.4.609 [Abstract] [PDF] [Request Permissions]  

Jerry W. Hussong, Peter J. Polverini, and Dennis B. Solt

Resistant keratinocytes in 7,12-dimethylbenz[a]anthracene-initiated hamster buccal pouch epithelium
Carcinogenesis 1991 12: 617-622; doi:10.1093/carcin/12.4.617 [Abstract] [PDF] [Request Permissions]  

Nobuo Nemoto, Junko Sakurai, Ayumi Tazawa, and Takatoshi Ishikawa

Regulation of mouse P₁450 gene expression in monolayer-cultured hepatocytes from responsive and non-responsive strains
Carcinogenesis 1991 12: 623-629; doi:10.1093/carcin/12.4.623 [Abstract] [PDF] [Request Permissions]  

Clive A. Smith

Chemical synthesis of oligonucleotides containing a naphthalene diolepoxide deoxycytidine adduct in solution and using a mixed chemistry semi-automated solid phase approach
Carcinogenesis 1991 12: 631-636; doi:10.1093/carcin/12.4.631 [Abstract] [PDF] [Request Permissions]  

G.A. Tejwani, K.P. Gudehithlu, S.H. Hanissian, I.E. Gienapp, C.C. Whitacre, and W.B. Malarkey

Facilitation of dimethylbenz[a]anthracene-induced rat mammary tumorigenesis by restraint stress: role of ß-endorphin, prolactin and naltrexone
Carcinogenesis 1991 12: 637-641; doi:10.1093/carcin/12.4.637 [Abstract] [PDF] [Request Permissions]  

Peter M. Eckl, Teresa Alati, and Randy L. Jirtle

The effects of a purified diet on sister chromatid exchange frequencies and mitotic activity in adult rat hepatocytes
Carcinogenesis 1991 12: 643-646; doi:10.1093/carcin/12.4.643 [Abstract] [PDF] [Request Permissions]  

Lisa A.E. Kaplan, Mary E. Schultz, R.Jack Schultz, and J.F. Crivello

Nitrosodiethylamine metabolism in the viviparous fish Poeciliopsis: evidence for the existence of liver P450pj activity and expression
Carcinogenesis 1991 12: 647-652; doi:10.1093/carcin/12.4.647 [Abstract] [PDF] [Request Permissions]  

Paul C. Billings, Tina Jin, Noriko Ohnishi, David C. Liao, and Joan M. Habres

The interaction of the potato-derived chymotrypsin inhibitor with C3H/10T1/2 cells
Carcinogenesis 1991 12: 653-657; doi:10.1093/carcin/12.4.653 [Abstract] [PDF] [Request Permissions]  

A. Marino, N. Ravelingien, D. De Cannière, V. Prèat, J.P. Dehaye, and J.C. Pector

Adenylate cyclase activity in crude liver membranes during chemical hepatocarcinogenesis
Carcinogenesis 1991 12: 659-664; doi:10.1093/carcin/12.4.659 [Abstract] [PDF] [Request Permissions]  

Nicholas M. Dean, Lawrence J. Mordan, Kathy Tse, Susan L. Mooberry, and Alton L. Boynton

Okadaic acid inhibits PDGF-induced proliferation and decreases PDGF receptor number in C3H/10T1/2 mouse fibroblasts
Carcinogenesis 1991 12: 665-670; doi:10.1093/carcin/12.4.665 [Abstract] [PDF] [Request Permissions]  

John S. Bertram, Ao Pung, Melissa Churley, T. Joseph Kappock, IV, Lynne R. Wilkins, and Robert V. Cooney

Diverse carotenoids protect against chemically induced neoplastic transformation
Carcinogenesis 1991 12: 671-678; doi:10.1093/carcin/12.4.671 [Abstract] [PDF] [Request Permissions]  

Susan W. Edmondson and Brooke T. Mossman

Alteration in keratin expression in hamster tracheal epithelial cells exposed to benzo[a]pyrene
Carcinogenesis 1991 12: 679-684; doi:10.1093/carcin/12.4.679 [Abstract] [PDF] [Request Permissions]  

N. Matsukura, J. Willey, M. Miyashita, B. Taffe, D. Hoffmann, C. Waldren, T.T. Puck, and C.C. Harris

Detection of direct mutagenicity of cigarette smoke condensate in mammalian cells
Carcinogenesis 1991 12: 685-689; doi:10.1093/carcin/12.4.685 [Abstract] [PDF] [Request Permissions]  

Ja June Jang, Kyung Ja Cho, Yun Sil Lee, and Jong Hee Bae

Modifying responses of allyl sulfide, indole-3-carbinol and germanium in a rat multi-organ carcinogenesis model
Carcinogenesis 1991 12: 691-695; doi:10.1093/carcin/12.4.691 [Abstract] [PDF] [Request Permissions]  

Antal K.D. Hajos and Gary W. Winston

Dinitropyrene nitroreductase activity of purified NAD(P)H-quinone oxidoreductase: role in rat liver cytosol and induction by Aroclor-1254 pretreatment
Carcinogenesis 1991 12: 697-702; doi:10.1093/carcin/12.4.697 [Abstract] [PDF] [Request Permissions]  

Kazushige Morimoto, Kazuhiko Tsuji, Toshihiro Iio, Naoki Miyata, Akiko Uchida, Ryoichi Osawa, Hiroshi Kitsutaka, and Atsuhi Takahashi

DNA damage in forestomach epithelium from male F344 rats following oral administration of tert-butylquinone, one of the forestomach metabolites of 3-BHA
Carcinogenesis 1991 12: 703-708; doi:10.1093/carcin/12.4.703 [Abstract] [PDF] [Request Permissions]  

A.C. Povey, D.P. Cooper, and E. Littler

³²P-Postabelling of alkylated thymidines using Epstein-Barr virus encoded thymidin kinase
Carcinogenesis 1991 12: 709-712; doi:10.1093/carcin/12.4.709 [Abstract] [PDF] [Request Permissions]  

Marco Peluso, Marcel Castegnaro, Christian Malaveille, Marlin Friesen, Liliane Garren, Agnès Hautefeuille, Paolo Vineis, Fred Kadlubar, and Helmut Bartsch

³²Postabelling analysis of urinary mutagens from smokers of black tobacco implicates 2-amino-1-methyl-6-phnylimidazo[4,5-b]pyridine (PhIP) as a major DNA-damaging agent
Carcinogenesis 1991 12: 713-717; doi:10.1093/carcin/12.4.713 [Abstract] [PDF] [Request Permissions]  

Ayumi Denda, Kimie Sai, Qing Tang, Toshifumi Tsujiuchi, Masahiro Tsutsumi, Toshihiro Amanuma, Yoshiharu Murata, Dai Nakae, Hiroshi Maruyama, Yuji Kurokawa, and Yoichi Konishi

Induction of 8-hydroxydeoxyguanosine but not initiation of carcinogenesis by redox enzyme modulations with or without menadione in rat liver
Carcinogenesis 1991 12: 719-726; doi:10.1093/carcin/12.4.719 [Abstract] [PDF] [Request Permissions]  

P.M. Potter, J.A. Rafferty, L. Cawkwell, M.C. Wilkinson, D.P. Cooper, P.J. O'Connor, and G.P. Margison

Isolation and cDNA cloning of a rat; O⁶-alkyllguanine-DNA-alkyltransferase gene, molecelar analysis of expression in rat liver
Carcinogenesis 1991 12: 727-733; doi:10.1093/carcin/12.4.727 [Abstract] [PDF] [Request Permissions]  

SHORT COMMUNICATIONS:

Lawrence W. Updyke, Hyunah L. Yoon, and Richard W. Pfeifer

Induction of granulocyte-macrophage colony-sitmulating activity toy 12-O-tetradecanoylphobol-13-acetate in SENCAR and B6C3F1 mice
Carcinogenesis 1991 12: 735-739; doi:10.1093/carcin/12.4.735 [Abstract] [PDF] [Request Permissions]  

Joanne C. Harrison and R. Colin Garner

Immunological and HPLC detection of aflatoxin adducts in human tissues after an acute poisoning incident in S.E. Asia
Carcinogenesis 1991 12: 741-743; doi:10.1093/carcin/12.4.741 [Abstract] [PDF] [Request Permissions]  

B. Singer, J.T. Kusmierek, W. Folkman, F. Chavez, and M.K. Dosanjh

Evidence for the mutagenic potential of the vinyl chloride induced added, N², 3-etheno-deoxyguanosine, using a site-directed kinetic assay
Carcinogenesis 1991 12: 745-747; doi:10.1093/carcin/12.4.745 [Abstract] [PDF] [Request Permissions]  

Announcement:

Genetic and epigenetic determinants of premalignant and malignant phenotype
Carcinogenesis 1991 12: 749; doi:10.1093/carcin/12.4.749 [PDF] [Request Permissions]  

Author index:

Author index
Carcinogenesis 1991 12: 750; doi:10.1093/carcin/12.4.750 [PDF] [Request Permissions]  

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