Carcinogenesis

ACCELERATED PAPER:

Nasir H. Zaidi, Christopher S. Potten, Geoffrey P. Margison, Donald P. Cooper, and Peter J. O'Connor

Tissue and cell specific methylation, repair and synthesis of DNA in the upper gastrointestinal tract of Wistar rats treated with single doses of N-methyl-N'-nitro-N-nitrosoguanidine
Carcinogenesis 1993 14: 1981-1990; doi:10.1093/carcin/14.10.1981 [Abstract] [PDF] [Request Permissions]  

Nasir H. Zaidi, Christopher S. Potten, Geoffrey P. Margison, Donald P. Cooper, and Peter J. O'Connor

Tissue and cell specific methylation, repair and synthesis of DNA in the upper gastrointestinal tract of Wistar rats treated with N-methyl-N'-nitro-N-nitrosoguanidine via the drinking water
Carcinogenesis 1993 14: 1991-2001; doi:10.1093/carcin/14.10.1991 [Abstract] [PDF] [Request Permissions]  

John P. Vanden Heuvel, George C. Clark, Claudia L. Thompson, Zadock McCoy, Chris R. Miller, George W. Lucier, and Douglas A. Bell

CYP1A1 mRNA levels as a human exposure biomarker: use of quantitative polymerase chain reaction to measure CYP1A1 expression in human peripheral blood lymphocytes
Carcinogenesis 1993 14: 2003-2006; doi:10.1093/carcin/14.10.2003 [Abstract] [PDF] [Request Permissions]  

COMMENTARY:

Kari Hemminki

DNA adducts, mutations and cancer
Carcinogenesis 1993 14: 2007-2012; doi:10.1093/carcin/14.10.2007 [Abstract] [PDF] [Request Permissions]  

ORIGINAL ARTICLES:

Üzen Savas, Maro Christou, and Colin R. Jefcoate

Mouse endometrium stromal cells express a polycyclic aromatic hydrocarbon-inducible cytochrome P450 that closely resembles the novel P450 in mouse embryo fibroblasts (P450EF)
Carcinogenesis 1993 14: 2013-2018; doi:10.1093/carcin/14.10.2013 [Abstract] [PDF] [Request Permissions]  

Konstantin Christov, Steven M. Swanson, Raphael C. Guzman, Gudmundar Thordarson, Edward Jin, Frank Talamantes, and Satyabrata Nandi

Kinetics of mammary epithelial cell proliferation in pituitary isografted BALB/c mice
Carcinogenesis 1993 14: 2019-2025; doi:10.1093/carcin/14.10.2019 [Abstract] [PDF] [Request Permissions]  

Kerstin Skog and Margaretha Jägerstad

Incorporation of carbon atoms from glucose into the food mutagens MeIQx and 4,8-DiMeIQx using ¹⁴C-labelled glucose in a model system
Carcinogenesis 1993 14: 2027-2031; doi:10.1093/carcin/14.10.2027 [Abstract] [PDF] [Request Permissions]  

Shantu Amin, Dhimant Desai, and Stephen S. Hecht

Tumor-initiating activity on mouse skin of bay region diol-epoxides of 5,6-dimethylchrysene and benzo[c]phenanthrene
Carcinogenesis 1993 14: 2033-2037; doi:10.1093/carcin/14.10.2033 [Abstract] [PDF] [Request Permissions]  

A. Mentzschel, S. Vamvakas, W. Dekant, and D. Henschler

DNA adduct formation in Salmonella typhimurium, cultured liver cells and in Fischer 344 rats treated with o-tolyl phosphates and their metabolites
Carcinogenesis 1993 14: 2039-2043; doi:10.1093/carcin/14.10.2039 [Abstract] [PDF] [Request Permissions]  

DeZhong Liao, Inger Porsch-Hällström, Jan-Ake Gustafsson, and Agneta Blanck

Sex differences at the initiation stage of rat liver carcinogenesis—influence of growth hormone
Carcinogenesis 1993 14: 2045-2049; doi:10.1093/carcin/14.10.2045 [Abstract] [PDF] [Request Permissions]  

Phillip F. Pratt and Charles R. Myers

Enzymatic reduction of chromium(VI) by human hepatic microsomes
Carcinogenesis 1993 14: 2051-2057; doi:10.1093/carcin/14.10.2051 [Abstract] [PDF] [Request Permissions]  

Pavel Vodicka, Ludmila Vodickova, and Kari Hemminki

³²P-postlabeling of DNA adducts of styrene-exposed lamination workers
Carcinogenesis 1993 14: 2059-2061; doi:10.1093/carcin/14.10.2059 [Abstract] [PDF] [Request Permissions]  

Sherif A. Kafafi, Hussein Y. Afeefy, Ali H. Ali, Hakim K. Said, Ibrahim S. Abd-Elazem, and Abdel G. Kafafi

Affinities for the aryl hydrocarbon receptor, potencies as aryl hydrocarbon hydroxylase inducers and relative toxicities of polychlorinated biphenyls. A congener specific approach
Carcinogenesis 1993 14: 2063-2071; doi:10.1093/carcin/14.10.2063 [Abstract] [PDF] [Request Permissions]  

F.-L. Chung, H.-J.C. Chen, J.B. Guttenplan, A. Nishikawa, and G.C. Hard

2,3-Epoxy-4-hydroxynonanal as a potential tumor-initiating agent of lipid peroxidation
Carcinogenesis 1993 14: 2073-2077; doi:10.1093/carcin/14.10.2073 [Abstract] [PDF] [Request Permissions]  

S.R.R. Musk and I.T. Johnson

Allyl isothiocyanate is selectively toxic to transformed cells of the human colorectal tumour line HT29
Carcinogenesis 1993 14: 2079-2083; doi:10.1093/carcin/14.10.2079 [Abstract] [PDF] [Request Permissions]  

Svein-Ole Mikalsen

Heterologous gap junctional intercellular communication in normal and morphologically transformed colonies of Syrian hamster embryo cells
Carcinogenesis 1993 14: 2085-2090; doi:10.1093/carcin/14.10.2085 [Abstract] [PDF] [Request Permissions]  

Cindy D. Davis, Herman A.J. Schut, and Elizabeth G. Snyderwine

Enzymatic phase II activation of the N-hydroxylamines of IQ, MelQx and PhIP by various organs of monkeys and rats
Carcinogenesis 1993 14: 2091-2096; doi:10.1093/carcin/14.10.2091 [Abstract] [PDF] [Request Permissions]  

G. Aquilina, R. Biondo, E. Dogliotti, and M. Bignami

Genetic consequences of tolerance to methylation DNA damage in mammalian cells
Carcinogenesis 1993 14: 2097-2103; doi:10.1093/carcin/14.10.2097 [Abstract] [PDF] [Request Permissions]  

Miroslav Pirsel and Vilhelm A. Bohr

Methyl methanesulfonate adduct formation and repair in the DHFR gene and in mitochondrial DNA in hamster cells
Carcinogenesis 1993 14: 2105-2108; doi:10.1093/carcin/14.10.2105 [Abstract] [PDF] [Request Permissions]  

Eddie E. Li, Robert H. Heflich, and K. Barry Delclos

Trans-1,2-dihydro-1,2-dihydroxy-6-aminochrysene is metabolized to form a major adduct with deoxyguanosine and produces mutations in the hprt gene of Chinese hamster ovary cells at G:C basepairs
Carcinogenesis 1993 14: 2109-2114; doi:10.1093/carcin/14.10.2109 [Abstract] [PDF] [Request Permissions]  

Klaus Gjervig Jensen, Agneta Önfelt, Henrik E. Poulsen, Johannes Doehmer, and Steffen Loft

Effects of benzo[a]pyrene and (±)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene on mitosis in Chinese hamster V79 cells with stable expression of rat cytochrome P4501A1 or 1A2
Carcinogenesis 1993 14: 2115-2118; doi:10.1093/carcin/14.10.2115 [Abstract] [PDF] [Request Permissions]  

Iver Petersen, Hiroko Ohgaki, Barbara I. Ludeke, and Paul Kleihues

p53 mutations in phenacetin-associated human urothelial carcinomas
Carcinogenesis 1993 14: 2119-2122; doi:10.1093/carcin/14.10.2119 [Abstract] [PDF] [Request Permissions]  

Marika I. Kleman, Eva Övervik, Inger Porsch-Hällström, Agneta Blanck, and Jan-Ake Gustafsson

The heterocyclic amines IQ and MeIQx show no promotive effect in a short-term in vivo liver carcinogenesis assay
Carcinogenesis 1993 14: 2123-2125; doi:10.1093/carcin/14.10.2123 [Abstract] [PDF] [Request Permissions]  

E. Leibold and L.R. Schwarz

Intercellular communication in primary cultures of putative preneoplastic and ‘normal’ hepatocytes
Carcinogenesis 1993 14: 2127-2129; doi:10.1093/carcin/14.10.2127 [Abstract] [PDF] [Request Permissions]  

Michaë E.T.I. Boerrigter, Claudio Franceschi, Eduardo Arrigoni-Martelli, Jeanne Y. Wei, and Jan Vijg

The effect of L-carnitine and acetyl-L-carnitine on the disappearance of DNA single-strand breaks in human peripheral blood lymphocytes
Carcinogenesis 1993 14: 2131-2136; doi:10.1093/carcin/14.10.2131 [Abstract] [PDF] [Request Permissions]  

Andrew M. Standeven and Thomas L. Goldsworthy

Promotion of preneoplastic lesions and induction of CYP2B by unleaded gasoline vapor in female B6C3F1 mouse liver
Carcinogenesis 1993 14: 2137-2141; doi:10.1093/carcin/14.10.2137 [Abstract] [PDF] [Request Permissions]  

Dan Segerbäck, Keith R. Kaderlik, Glenn Talaska, Kenneth L. Dooley, and Fred F. Kadlubar

³²P-Postlabelling analysis of DNA adducts of 4,4'-methylenebis(2-chloroaniline) in target and nontarget tissues in the dog and their implications for human risk assessment
Carcinogenesis 1993 14: 2143-2147; doi:10.1093/carcin/14.10.2143 [Abstract] [PDF] [Request Permissions]  

Gary M. Williams, Rolf Gebhardt, Hüseyin Sirma, and Frej Stenbäck

Non-linearity of neoplastic conversion induced in rat liver by low exposures to diethylnitrosamine
Carcinogenesis 1993 14: 2149-2156; doi:10.1093/carcin/14.10.2149 [Abstract] [PDF] [Request Permissions]  

Hiroshi Inano, Keiko Suzuki, Hiroko Ishii-Ohba, Hiroshi Yamanouchi, Masakazu Takahashi, and Katsumi Wakabayashi

Promotive effects of diethylstilbestrol, its metabolite (Z,Z-dienestrol) and a stereoisomer of the metabolite (E,E-dienestrol) in tumorigenesis of rat mammary glands pregnancy-dependently initiated with radiation
Carcinogenesis 1993 14: 2157-2163; doi:10.1093/carcin/14.10.2157 [Abstract] [PDF] [Request Permissions]  

Masako Ochiai, Hiroaki Nagaoka, Keiji Wakabayashi, Yoshino Tanaka, Seon-Bong Kim, Akihiro Tada, Haruo Nukaya, Takashi Sugimura, and Minako Nagao

Identification of N²-(deoxyguanosin-8-yl)-2-amino-3,8-dimethylimidazo[4,5-f)quinoxaline 3',5'-diphosphate, a major DNA adduct, detected by nuclease P1 modification of the ³²P-postlabeling method, in the liver of rats fed MeIQx
Carcinogenesis 1993 14: 2165-2170; doi:10.1093/carcin/14.10.2165 [Abstract] [PDF] [Request Permissions]  

Masaru Sugiyama, Paul M. Speight, Stephen S. Prime, and Fiona M. Watt

Comparison of integrin expression and terminal differentiation capacity in cell lines derived from oral squamous cell carcinomas
Carcinogenesis 1993 14: 2171-2176; doi:10.1093/carcin/14.10.2171 [Abstract] [PDF] [Request Permissions]  

Kang Bo Lee, Ricardo J. Parker, Vilhelm Bohr, Terri Cornelison, and Eddie Reed

Cisplatin sensitivity/resistance in UV repair-deficient Chinese hamster ovary cells of complementation groups 1 and 3
Carcinogenesis 1993 14: 2177-2180; doi:10.1093/carcin/14.10.2177 [Abstract] [PDF] [Request Permissions]  

SHORT COMMUNICATIONS:

Adelaide M. Carothers, Gail Urlaub, Jitka Mucha, Wei Yuan, Lawrence A. Chasin, and Dezider Grunberger

A mutational hot spot induced by N-hydroxy-aminofluorene in dihydrofolate reductase mutants of Chinese hamster ovary cells
Carcinogenesis 1993 14: 2181-2184; doi:10.1093/carcin/14.10.2181 [Abstract] [PDF] [Request Permissions]  

Alberto Izzotti, Maria Bagnasco, Leonardo Scatolini, Alessandra Rovida, and Silvio De Flora

Post-mortem stability of benzo[a]pyrene diolepoxide-DNA adducts in rat organs
Carcinogenesis 1993 14: 2185-2187; doi:10.1093/carcin/14.10.2185 [Abstract] [PDF] [Request Permissions]  

Weigong Zhou, Stephen P. Povoski, and Richard H. Bell, Jr

Overexpression of messenger RNA for cholecystokinin-A receptor and novel expression of messenger RNA for gastrin (cholecystokinin-B) receptor in azaserine-induced rat pancreatic carcinoma
Carcinogenesis 1993 14: 2189-2192; doi:10.1093/carcin/14.10.2189 [Abstract] [PDF] [Request Permissions]  

Charareh Pourzand and Peter Cerutti

Mutagenesis of H-ras codons 11 and 12 in human fibroblasts by N-ethyl-N-nitrosourea
Carcinogenesis 1993 14: 2193-2196; doi:10.1093/carcin/14.10.2193 [Abstract] [PDF] [Request Permissions]  

Announcement:

Announcement
Carcinogenesis 1993 14: 2197; doi:10.1093/carcin/14.10.2197 [PDF] [Request Permissions]  

Author index:

Author index
Carcinogenesis 1993 14: 2198; doi:10.1093/carcin/14.10.2198 [PDF] [Request Permissions]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.