Carcinogenesis

ACCELERATED PAPER:

Michael N. Routledge, David A. Wink, Larry K. Keefer, and Anthony Dipple

Mutations induced by saturated aqueous nitric oxide in the pSP189 supF gene in human Ad293 and E. coli MBM7070 cells
Carcinogenesis 1993 14: 1251-1254; doi:10.1093/carcin/14.7.1251 [Abstract] [PDF] [Request Permissions]  

ORIGINAL ARTICLES:

Catherine Madzak, Jacques Armier, Anne Stary, Leela Daya-Grosjean, and Alain Sarasin

UV-induced mutations in a shuttle vector replicated in repair deficient trichothiodystrophy cells differ with those in genetically-related cancer prone xeroderma pigmentosum
Carcinogenesis 1993 14: 1255-1260; doi:10.1093/carcin/14.7.1255 [Abstract] [PDF] [Request Permissions]  

Mirjana Zarkovic, Xiusheng Qin, Yoko Nakatsuru, Hideaki Oda, Takuro Nakamura, Abulkalam M. Shamsuddin, and Takatoshi Ishikawa

Tumor promotion by fecapentaene-12 in a rat colon carcinogenesis model
Carcinogenesis 1993 14: 1261-1264; doi:10.1093/carcin/14.7.1261 [Abstract] [PDF] [Request Permissions]  

Masa-Aki Shibata, Masao Hirose, Atsuko Masuda, Toshio Kato, Mamoru Mutai, and Nobuyuki Ito

Modification of BHA forestomach carcinogenesis in rats: inhibition by diethylmaleate or indomethacin and enhancement by a retinoid
Carcinogenesis 1993 14: 1265-1269; doi:10.1093/carcin/14.7.1265 [Abstract] [PDF] [Request Permissions]  

Hiroshi Yamazaki, Mayumi Mimura, Yoshimitsu Oda, Yukiharu Inui, Toshifumi Shiraga, Kazuhide Iwasaki, F. Peter Guengerich, and Tsutomu Shimada

Roles of different forms of cytochrome P450 in the activation of the promutagen 6-aminochrysene to genotoxic metabolites in human liver microsomes
Carcinogenesis 1993 14: 1271-1278; doi:10.1093/carcin/14.7.1271 [Abstract] [PDF] [Request Permissions]  

Francois Janot, Liliane Massaad, Vincent Ribrag, Isabelle de Waziers, Philippe H. Beaune, Bernard Luboinski, Orlando Parise, Jr, Alain Gouyette, and Guy G. Chabot

Principal xenobiotic-metabolizing enzyme systems in human head and neck squamous cell carcinoma
Carcinogenesis 1993 14: 1279-1283; doi:10.1093/carcin/14.7.1279 [Abstract] [PDF] [Request Permissions]  

Wolfgang H. Fischer, Peter E. Beland, and Werner K. Lutz

DNA adducts, cell proliferation and papilloma latency time in mouse skin after repeated dermal application of DMBA and TPA
Carcinogenesis 1993 14: 1285-1288; doi:10.1093/carcin/14.7.1285 [Abstract] [PDF] [Request Permissions]  

S.A.L. Bennett, L.C.C. Leite, and H.C. Birnboim

Platelet activating factor, an endogenous mediator of inflammation, induces phenotypic transformation of rat embryo cells
Carcinogenesis 1993 14: 1289-1296; doi:10.1093/carcin/14.7.1289 [Abstract] [PDF] [Request Permissions]  

P.A.E.L. Schilderman, J.M.S. van Maanen, F.J.ten Vaarwerk, M.V.M. Lafleur, E.J. Westmijze, F. ten Hoor, and J.C.S. Kleinjans

The role of prostaglandin H synthase-mediated metabolism in the induction of oxidative DNA damage by BHA metabolites
Carcinogenesis 1993 14: 1297-1302; doi:10.1093/carcin/14.7.1297 [Abstract] [PDF] [Request Permissions]  

Yunbo Li and Michael A. Trush

DNA damage resulting from the oxidation of hydroquinone by copper: role for a Cu(II)/Cu(I) redox cycle and reactive oxygen generation
Carcinogenesis 1993 14: 1303-1311; doi:10.1093/carcin/14.7.1303 [Abstract] [PDF] [Request Permissions]  

Yvonne P. Dragan, Jodi Peterson, and Henry C. Pitot

Comparison of hepatocyte phenotypes at the glutathione transferase and albumin loci in Sprague-Dawley and Nagase analbuminemic rats and F1 progeny after initiation and promotion
Carcinogenesis 1993 14: 1313-1319; doi:10.1093/carcin/14.7.1313 [Abstract] [PDF] [Request Permissions]  

Takuji Tanaka, Toshihiro Kojima, Toshihiko Kawamori, Aijin Wang, Masumi Suzui, Kiyohisa Okamoto, and Hideki Mori

Inhibition of 4-nitroquinoline-1-oxide-induced rat tongue carcinogenesis by the naturally occurring plant phenolics caffeic, ellagic, chlorogenic and ferulic acids
Carcinogenesis 1993 14: 1321-1325; doi:10.1093/carcin/14.7.1321 [Abstract] [PDF] [Request Permissions]  

Chinthalapally V. Rao and Bandaru S. Reddy

Modulating effect of amount and types of dietary fat on ornithine decarboxylase, tyrosine protein kinase and prostaglandins production during colon carcinogenesis in male F344 rats
Carcinogenesis 1993 14: 1327-1333; doi:10.1093/carcin/14.7.1327 [Abstract] [PDF] [Request Permissions]  

Judson W. Spalding, Junko Momma, Michael R. Elwell, and Raymond W. Tennant

Chemically induced skin carcinogenesis in a transgenic mouse line (TG·AC) carrying a v-Ha-ras gene
Carcinogenesis 1993 14: 1335-1341; doi:10.1093/carcin/14.7.1335 [Abstract] [PDF] [Request Permissions]  

L. Möller, M. Zeisig, and P. Vodicka

Optimization of an HPLC method for analyses of ³²P-postlabeled DNA adducts
Carcinogenesis 1993 14: 1343-1348; doi:10.1093/carcin/14.7.1343 [Abstract] [PDF] [Request Permissions]  

Masahiko Hirota, Parviz M. Pour, and William G. Chaney

UDP-GalNAc:Fuc1–2Gal1–3GalNAc transferase activity in hamster pancreatic cancers and in normal hamster alimentary tissues
Carcinogenesis 1993 14: 1349-1353; doi:10.1093/carcin/14.7.1349 [Abstract] [PDF] [Request Permissions]  

Mami Takahashi, Toshinari Minamoto, Tokashi Sugimura, and Hiroyasu Esumi

High frequency and low specificity of ras gene mutations in rat Zymbal's gland tumors induced by 2-amino-3-methylimidazo[4, 5-f]quinoline
Carcinogenesis 1993 14: 1355-1357; doi:10.1093/carcin/14.7.1355 [Abstract] [PDF] [Request Permissions]  

En-Hua Cao and Ju-Jun Wang

Oxidative damage to DNA: levels of thymine glycol and thymidine glycol in neoplastic human urines
Carcinogenesis 1993 14: 1359-1362; doi:10.1093/carcin/14.7.1359 [Abstract] [PDF] [Request Permissions]  

J.M. Yates, S.C.J. Sumner, M.J. Turner, Jr, L. Recio, and T.R. Fennell

Characterization of an adduct and its degradation product produced by the reaction of cyanoethylene oxide with deoxythymidine and DNA
Carcinogenesis 1993 14: 1363-1369; doi:10.1093/carcin/14.7.1363 [Abstract] [PDF] [Request Permissions]  

Tony P. Simula, Michael J. Glancey, and C. Roland Wolf

Human glutathione S-transferase-expressing Salmonella typhimurium tester strains to study the activation/detoxification of mutagenic compounds: studies with halogenated compounds, aromatic amines and aflatoxin B₁
Carcinogenesis 1993 14: 1371-1376; doi:10.1093/carcin/14.7.1371 [Abstract] [PDF] [Request Permissions]  

Wilbert H.M. Peters, Theo Wobbes, Hennie M.J. Roelofs, and Jan B.M.J. Jansen

Glutathione S-transferases in esophageal cancer
Carcinogenesis 1993 14: 1377-1380; doi:10.1093/carcin/14.7.1377 [Abstract] [PDF] [Request Permissions]  

Andrew G. Smith, Philip Carthew, Jean E. Francis, J.Ricardo P. Cabral, and Margaret M. Manson

Enhancement by iron of hepatic neoplasia in rats caused by hexachlorobenzene
Carcinogenesis 1993 14: 1381-1387; doi:10.1093/carcin/14.7.1381 [Abstract] [PDF] [Request Permissions]  

Elizabeth G. Snyderwine, Cindy D. Davis, Kazuhiro Nouso, Peter P. Roller, and Herman A.J. Schut

³²P-Postlabeling analysis of IQ, MelQx and PhIP adducts formed in vitro in DNA and polynucleotides and found in vivo in hepatic DNA from IQ-, MelQx- and PhIP-treated monkeys
Carcinogenesis 1993 14: 1389-1395; doi:10.1093/carcin/14.7.1389 [Abstract] [PDF] [Request Permissions]  

Koji Yamamoto, Sumiko Inoue, and Shosuke Kawanishi

Site-specific DNA damage and 8-hydroxydeoxyguanosine formation by hydroxylamine and 4- hydroxyaminoquinoline 1-oxide in the presence of Cu(II): Role of active oxygen species
Carcinogenesis 1993 14: 1397-1404; doi:10.1093/carcin/14.7.1397 [Abstract] [PDF] [Request Permissions]  

Valentia M. Lee, Ross G. Cameron, and Michael C. Archer

The role of hepatocyte heterogeneity in the initiation of hepatocarcinogenesis
Carcinogenesis 1993 14: 1403-1408; doi:10.1093/carcin/14.7.1403 [Abstract] [PDF] [Request Permissions]  

Anthony R. Tricker, Gerhard Scherer, Charlotte Conze, Franz Adlkofer, Anton Pachinger, and Hubert Klus

Evaluation of 4-(N-methylnitrosamino)-4-(3-pyridyl)butyric acid as a potential monitor of endogenous nitrosation of nicotine and its metabolites
Carcinogenesis 1993 14: 1409-1414; doi:10.1093/carcin/14.7.1409 [Abstract] [PDF] [Request Permissions]  

Masae Tatematsu, Masao Ichinose, Shinko Tsukada, Nobuyuki Kakei, Satoru Takahashi, Kumiko Ogawa, Masao Hirose, Chie Furihata, Kazumasa Miki, Kiyoshi Kurokawa, and Nobuyuki Ito

DNA mutilation of the pepsin 1 gene during rat glandular stomach carcinogensis induced by N-methyl-N'-nitro-N-nitrosoguanidine or catechol
Carcinogenesis 1993 14: 1415-1419; doi:10.1093/carcin/14.7.1415 [Abstract] [PDF] [Request Permissions]  

Howard F. Tiano, Masakiyo Hosokawa, Patricia C. Chulada, P.Blaise Smith, Ren-Li Wang, Frank J. Gonzalez, Charles L. Crespi, and Robert Langenbach

Retroviral mediated expression of human cytochrome P450 2A6 in C3H/10T1/2 cells confers transformability by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)
Carcinogenesis 1993 14: 1421-1427; doi:10.1093/carcin/14.7.1421 [Abstract] [PDF] [Request Permissions]  

Jonathan M. Daniels, Tibor I. Matula, and Thomas E. Massey

DNA binding and mutagenicity of aflatoxin B₁ catalyzed by isolated rabbit lung cells
Carcinogenesis 1993 14: 1429-1434; doi:10.1093/carcin/14.7.1429 [Abstract] [PDF] [Request Permissions]  

Charles C. Kiehlbauch, Stanley D. Kosanke, and David P. Ringer

Changes in levels of ADP-ribose polymers in rat liver during 2-acetylaminofluorene-induced hepatocarcinogenesis
Carcinogenesis 1993 14: 1435-1440; doi:10.1093/carcin/14.7.1435 [Abstract] [PDF] [Request Permissions]  

Susan J. Land, Kim Zukowski, Mei-Sie Lee, Ching Y. Wang, and Charles M. King

Purification and characterization of a rat hepatic acetyltransferase that can metabolize aromatic amine derivatives
Carcinogenesis 1993 14: 1441-1449; doi:10.1093/carcin/14.7.1441 [Abstract] [PDF] [Request Permissions]  

N.C. Barrass, R.J. Price, B.G. Lake, and T.C. Orton

Comparison of the acute and chronic mitogenic effects of the peroxisome proliferators methylclofenapate and clofibric acid in rat liver
Carcinogenesis 1993 14: 1451-1456; doi:10.1093/carcin/14.7.1451 [Abstract] [PDF] [Request Permissions]  

Yi Sun, Larry W. Oberley, Terry D. Oberley, James H. Elwell, and Elaine Sierra-Rivera

Lowered antioxidant enzymes in spontaneously transformed embryonic mouse liver cells in culture
Carcinogenesis 1993 14: 1457-1463; doi:10.1093/carcin/14.7.1457 [Abstract] [PDF] [Request Permissions]  

SHORT COMMUNICATION:

George P. Ford and Bingze Wang

The updated electrostatic potential for cytosine completes the qualitative explanations of base alkylation regiochemistry
Carcinogenesis 1993 14: 1465-1467; doi:10.1093/carcin/14.7.1465 [Abstract] [PDF] [Request Permissions]  

Prathima Gopalan, Kojiro Tsuji, Kiyoko Lehmann, Masatomo Kimura, Hisashi Shinozuka, Kiyomi Sato, and Prabhakar D. Lotlikar

Modulation of aflatoxin B1-induced glutathione S-transferase placental form positive hepatic foci by pretreatment of rats with phenobarbital and buthionine sulfoximine
Carcinogenesis 1993 14: 1469-1470; doi:10.1093/carcin/14.7.1469 [Abstract] [PDF] [Request Permissions]  

Hiroko Ohgaki, Fumio Furukawa, Michihito Takahashi, and Paul Kleihues

K-ras mutations are frequent in pulmonary squamous cell carcinomas but not in adenocarcinomas of WBN/Kob rats induced by N-nitrosobis(2-oxopropyl)amine
Carcinogenesis 1993 14: 1471-1473; doi:10.1093/carcin/14.7.1471 [Abstract] [PDF] [Request Permissions]  

Toshio Mori, Kayoko Shimoi, Yu F. Sasaki, Keiji Wakabayashi, Minako Nagao, and Naohide Kinae

3-Amino-1, 4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) inhibits the removal of both cyclobutane dimers and (6–4) photoproducts from the DNA of ultraviolet-irradiated E. coli
Carcinogenesis 1993 14: 1475-1478; doi:10.1093/carcin/14.7.1475 [Abstract] [PDF] [Request Permissions]  

Ari Hirvonen, Kirsti Husgafvel-Pursiainen, Sisko Anttila, and Harri Vainio

The GSTM1 null genotype as a potential risk modifier for squamous cell carcinoma of the lung
Carcinogenesis 1993 14: 1479-1481; doi:10.1093/carcin/14.7.1479 [Abstract] [PDF] [Request Permissions]  

Mieko Okamoto, Hiroshi Ohtsu, Michiko Miyaki, and Hiromichi Yonekawa

No allelic loss at the p53 locus in 1,2-dimethylhydrazine-induced mouse colon tumors: PCR-SSCP analysis with sequence-tagged microsatellite site primers
Carcinogenesis 1993 14: 1483-1486; doi:10.1093/carcin/14.7.1483 [Abstract] [PDF] [Request Permissions]  

Richard C. Moon, Gary J. Kelloff, Carol J. Detrisac, Vernon E. Steele, Cathy F. Thomas, and Caroline C. Sigman

Chemoprevention of OH-BBN-induced bladder cancer in mice by piroxicam
Carcinogenesis 1993 14: 1487-1489; doi:10.1093/carcin/14.7.1487 [Abstract] [PDF] [Request Permissions]  

Errata:

Robert A. Koza, Michael J. Moore, and John J. Stegeman

Elevated ornithine decarboxylase activity, polyamines and cell proliferation in neoplastic and vacuolated liver cells of winter flounder (Pleuronectes americanus)
Carcinogenesis 1993 14: 1490-1491; doi:10.1093/carcin/14.7.1490 [Abstract] [PDF] [Request Permissions]  

Announcement:

Announcement
Carcinogenesis 1993 14: 1490; doi:10.1093/carcin/14.7.1490-a [PDF] [Request Permissions]  

Author index:

Author index
Carcinogenesis 1993 14: 1492; doi:10.1093/carcin/14.7.1492 [PDF] [Request Permissions]  

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