Carcinogenesis

ACCELERATED PAPERS:

David H. Phillips, Alan Hewer, Ian N. H. White, and Peter B. Farmer

Co-chromatography of a tamoxifen epoxide-deoxyguanylic acid adduct with a major DNA adduct formed in the livers of tamoxifen-treated rats
Carcinogenesis 1994 15: 793-795; doi:10.1093/carcin/15.5.793 [Abstract] [PDF] [Request Permissions]  

K. Randerath, Jia Bi, Nathalie Mabon, Padmavathi Sriram, and Bhagavatula Moorthy

Strong intensification of mouse hepatic tamoxifen DNA adduct formation by pretreatment with the sulfotransferase inhibitor and ubiquitous environmental pollutant pentachlorophenol
Carcinogenesis 1994 15: 797-800; doi:10.1093/carcin/15.5.797 [Abstract] [PDF] [Request Permissions]  

Shin-ichi Hayashi, Junko Watanabe, Kei Nakachi, Hidetaka Eguchi, Osamu Gotoh, and kaname Kawajiri

Interindividual difference in expression of human Ah receptor and related P450 genes
Carcinogenesis 1994 15: 801-806; doi:10.1093/carcin/15.5.801 [Abstract] [PDF] [Request Permissions]  

R. J. Graves, C. Coutts, H. Eyton-Jones, and T. Green

Relationship between hepatic DNA damage and methylene chloride-induced hepatocarcinogenicity in B6C3F1 mice
Carcinogenesis 1994 15: 991-996; doi:10.1093/carcin/15.5.991 [Abstract] [PDF] [Request Permissions]  

Xueliang Han and Joachiin G. Liehr

DNA single-strand breaks in kidneys of Syrian hamsters treated with steroidal estrogens: hormone-induced free radical damage preceding renal malignancy
Carcinogenesis 1994 15: 997-1000; doi:10.1093/carcin/15.5.997 [Abstract] [PDF] [Request Permissions]  

Zigang Dong, Joan L. Cmarik, Edmund J. Wendel, and Nancy H. Colburn

Differential transformation efficiency but not AP-1 induction under anchorage-dependent and -independent conditions
Carcinogenesis 1994 15: 1001-1004; doi:10.1093/carcin/15.5.1001 [Abstract] [PDF] [Request Permissions]  

William B. Coleman, David B. Throneburg, Joe W. Grisham, and Gary J. Smith

Overexpression of c-K-ras, c-N-ras and transforming growth factor ß co-segregate with tumorigenicity in morphologically transformed C3H 10T1/2 cell lines
Carcinogenesis 1994 15: 1005-1012; doi:10.1093/carcin/15.5.1005 [Abstract] [PDF] [Request Permissions]  

Yue E. Chin, Elizabeth T. Snow, and Nelwyn T. Christie

The stimulatory effect of nickel chloride on DNA replication in human HeLa cells and Escherwhw coli
Carcinogenesis 1994 15: 1013-1016; doi:10.1093/carcin/15.5.1013 [Abstract] [PDF] [Request Permissions]  

Fredika M. Robertson, Gautam N. Bijur, Andrew S. Oberyszyn, Arthur E. Pellegrini, Laszlo G. Boros, L. K. Sabourin, and Tatiana M. Oberyszen

Granulocyte-macrophage colony stimulating factor gene expression and function during tumor promotion
Carcinogenesis 1994 15: 1017-1029; doi:10.1093/carcin/15.5.1017 [Abstract] [PDF] [Request Permissions]  

Paskasari A. Permana and Robert M. Snapka

Aldehyde-induced protein—DNA crosslinks disrupt specific stages of SV4I) DNA replication
Carcinogenesis 1994 15: 1031-1036; doi:10.1093/carcin/15.5.1031 [Abstract] [PDF] [Request Permissions]  

Ryohei Hasegawa, Emiko Miyata, Mitsuru Futakuchi, Akihiro Hagiwara, Minako Nagao, Takashi Sugimura, and Nobuyuki Ito

Synergistic enhancement of hepatic foci development by combined treatment of rats with 10 heterocyclic amines at low doses
Carcinogenesis 1994 15: 1037-1041; doi:10.1093/carcin/15.5.1037 [Abstract] [PDF] [Request Permissions]  

Giorgio Scita and George Wolf

Retinoic acid and beta-carotene inhibit fibronectin synthesis and release by fibroblasts; antagonism to phorbol ester
Carcinogenesis 1994 15: 1043-1048; doi:10.1093/carcin/15.5.1043 [Abstract] [PDF] [Request Permissions]  

Michael A. Pereira, Leta H. Barnes, Vicki L. Rassman, Gary V. Kelloff, and Vernon E. Steele

Use of azoxymethane-induced foci of aberrant crypts in rat colon to identify potential cancer chemopreventive agents
Carcinogenesis 1994 15: 1049-1054; doi:10.1093/carcin/15.5.1049 [Abstract] [PDF] [Request Permissions]  

ORIGINAL ARTICLES:

Hong Jiang, Satoshi Yamamoto, and Ryuichi Kato

Inhibition of two-stage skin carcinogenesis as well as complete skin carcinogenesis by oral administration of TMK688, a potent lipoxygenase inhibitor
Carcinogenesis 1994 15: 807-812; doi:10.1093/carcin/15.5.807 [Abstract] [PDF] [Request Permissions]  

Ari Hirvonen, Lars Nylund, Pirkko Kociba, Kirsti Husgafvel-Pursiainen, and Harri Vainio

Modulation of urinary mutagenicity by genetically determined carcinogen metabolism in smokers
Carcinogenesis 1994 15: 813-815; doi:10.1093/carcin/15.5.813 [Abstract] [PDF] [Request Permissions]  

Kathryn Z. Guyton, Patrick M. Dolan, and Thomas W. Kensler

Quinone methide mediates in vitro induction of ornithine decarboxylase by the tumor promoter butylated hydroxytoluene hydroperoxide
Carcinogenesis 1994 15: 817-821; doi:10.1093/carcin/15.5.817 [Abstract] [PDF] [Request Permissions]  

Anderson J. Ryan, Shoshana Squires, Helen L. Strutt, Amanda Evans, and Robert T. Johnson

Different fates of camptothecin-induced replication fork-associated double-strand DNA breaks in mammalian cells
Carcinogenesis 1994 15: 823-828; doi:10.1093/carcin/15.5.823 [Abstract] [PDF] [Request Permissions]  

Robert J. Edwards, Bernard P. Murray, Stephen Murray, Thomas Schulz, Dither Neubert, Timothy W. Gant, Snorri S. Thorgeirsson, Alan R. Boobis, and Donald S. Davies

Contribution of CYP1A1 and CYP1A2 to the activation of heterocyclic amines in monkeys and human
Carcinogenesis 1994 15: 829-836; doi:10.1093/carcin/15.5.829 [Abstract] [PDF] [Request Permissions]  

Christian Sengstag, Hans-Pietro Eugster, and Friedrich Würgler

High promutagen activating capacity of yeast microsomes containing human cytochrome P-450 1A and human NADPH-cytochrome P-450 reductase
Carcinogenesis 1994 15: 837-843; doi:10.1093/carcin/15.5.837 [Abstract] [PDF] [Request Permissions]  

E. Levy, C. Baroche, J. M. Barret, C. Alapetite, B. Salles, D. Averbeck, and E. Moustacchi

Activated ras oncogene and specifically acquired resistance to cisplatin in human mammary epithelial cells: induction of DNA cross-links and their repair
Carcinogenesis 1994 15: 845-850; doi:10.1093/carcin/15.5.845 [Abstract] [PDF] [Request Permissions]  

Xiusheng Qin, Mirjana Zarkovic, Yoko Nakatsuru, Masami Arai, Hideaki oda, and Takatoshi Ishikawa

DNA adduct formation and assessment of aberrant crypt foci in vivo in the rat colon mucosa after treatment with N-methyl-N-nitrosourea
Carcinogenesis 1994 15: 851-855; doi:10.1093/carcin/15.5.851 [Abstract] [PDF] [Request Permissions]  

L. Möller, M. Zeisig, T. Midtvedt, and J.-Å. Gustafsson

Intestinal microflora enhances formation of DNA adducts following administration of 2-NF and 2-AAF
Carcinogenesis 1994 15: 857-861; doi:10.1093/carcin/15.5.857 [Abstract] [PDF] [Request Permissions]  

Markku Ahotupa, Pirkko Hirsimäki, Raimo Päirssinen, and Eero Mäntylä

Alterations of drug metabolizing and antioxidant enzyme activities during tamoxifen-induced hepatocarcinogenesis in the rat
Carcinogenesis 1994 15: 863-868; doi:10.1093/carcin/15.5.863 [Abstract] [PDF] [Request Permissions]  

L. A. P. Ballering, M. J. M. Nivard, and E. W. Vogel

Mutation spectra of 1,2-dibromoethane, 1,2-dichloroethane and 1-bromo-2-chloroethane in excision repair proficient and repair deficient strains of Drosophila melanogaster
Carcinogenesis 1994 15: 869-875; doi:10.1093/carcin/15.5.869 [Abstract] [PDF] [Request Permissions]  

Wolfgang Pfau, Ulrike Brockstedt, Klaus-Dieter Söhren, and Hans Marquardt

³²P-Post-labelling analysis of DNA adducts formed by food-derived heterocyclic amines: evidence for incomplete hydrolysis and a procedure for adduct pattern simplification
Carcinogenesis 1994 15: 877-882; doi:10.1093/carcin/15.5.877 [Abstract] [PDF] [Request Permissions]  

Articles:

Sidney S. Mirvish, Dennis D. Weisenburger, Steven H. Hinrichs, Jeannetta Nickols, and Connie Hinman

Effect of catechol and ethanol with and without methylamylnitrosamine on esophageal carcinogenesis in the rat⁺
Carcinogenesis 1994 15: 883-887; doi:10.1093/carcin/15.5.883 [Abstract] [PDF] [Request Permissions]  

William B. Melchior, Jr, M. Matilde Marques, and Frederick A. Beland

Mutations induced by aromatic amine DNA adducts in pBR322
Carcinogenesis 1994 15: 889-899; doi:10.1093/carcin/15.5.889 [Abstract] [PDF] [Request Permissions]  

Atsushi Umemoto, Aiichiro Kajikawa, Masaki Tanaka, Kunimi Hamada, Mohammed Jabed Seraj, Akio Kubota, Masahiro Nakayama, Takemi Kinouchi, Yoshinari Ohnishi, Katsumi Yamashita, and Yasumasa Monden

Presence of mucosa-specific DNA adduct in human colon: possible implication for colorectal cancer
Carcinogenesis 1994 15: 901-905; doi:10.1093/carcin/15.5.901 [Abstract] [PDF] [Request Permissions]  

Hudson H.S. Lau and William M. Baird

Separation and characterization of post-labeled DNA adducts of stereoisomers of benzo[a]pyrene-7,8-diol-9,10-epoxide by immobilized boronate chromatography and HPLC analysis
Carcinogenesis 1994 15: 907-915; doi:10.1093/carcin/15.5.907 [Abstract] [PDF] [Request Permissions]  

Young-Joon Surh, Kwang-Kyun Park, and James A. Miller

Inhibitory effect of vitamin C on the mutagenicity and covalent DNA binding of the electrophilic and carcinogenic metabolite, 6-sulfooxymethylbenzo[a]pyrene
Carcinogenesis 1994 15: 917-920; doi:10.1093/carcin/15.5.917 [Abstract] [PDF] [Request Permissions]  

Inger Porsch Hällström, DeZhong Liao, Jan-Åke Gustafsson, and Agneta Blanck

Ectopic pituitary grafts modify the response of male rats to sex differentiated promotion of diethylnitrosamine-initiated hepatic lesions with a choline-deficient diet
Carcinogenesis 1994 15: 921-925; doi:10.1093/carcin/15.5.921 [Abstract] [PDF] [Request Permissions]  

Milind P. Niphadkar, Qais Q. Contractor, and Rajani A. Bhisey

Mutagenic activity of gastric fluid from chewers of tobacco with lime
Carcinogenesis 1994 15: 927-931; doi:10.1093/carcin/15.5.927 [Abstract] [PDF] [Request Permissions]  

J.S. Thomsen, X. Wang, R. N. Hines, and S. Safe

Restoration of aryl hydrocarbon (Ah) responsiveness in MDA-MB-231 human breast cancer cells by transient expression of the estrogen receptor
Carcinogenesis 1994 15: 933-937; doi:10.1093/carcin/15.5.933 [Abstract] [PDF] [Request Permissions]  

Jia-Ling Yang, Ping-Chuan Lee, Sing-Rong Lin, and Jin-Guo Lin

Comparison of mutation spectra induced by N-ethyl-N-nitrosourea in the hprt gene of Mer⁺ and Mer^– diploid human fibroblasts
Carcinogenesis 1994 15: 939-945; doi:10.1093/carcin/15.5.939 [Abstract] [PDF] [Request Permissions]  

Pia Larsson, Lief Busk, and Hans Tjälve

Hepatic and extrahepatic bioactivation and GSH conjugation of aflatoxin B₁ in sheep
Carcinogenesis 1994 15: 947-955; doi:10.1093/carcin/15.5.947 [Abstract] [PDF] [Request Permissions]  

Marie-José Durand and David E.G. Shuker

Preparation of compound-specific and group-specific antibodies to 7-methylguanine and related 7-alkylguanines and their use in immunoaffinity purification
Carcinogenesis 1994 15: 957-961; doi:10.1093/carcin/15.5.957 [Abstract] [PDF] [Request Permissions]  

James S. Steadman, Lester W. Lee, Gary J. Smith, and Joe W. Grisham

DNA contents and chromosomes of clonal lines of transformed rat liver epithelial cells and of cells from their derived tumors
Carcinogenesis 1994 15: 963-969; doi:10.1093/carcin/15.5.963 [Abstract] [PDF] [Request Permissions]  

G.A. Hart, L.M. Kathman, and T.W. Hesterberg

In vitro cytotoxicity of asbestos and man-made vitreous fibers: roles of fiber length, diameter and composition
Carcinogenesis 1994 15: 971-977; doi:10.1093/carcin/15.5.971 [Abstract] [PDF] [Request Permissions]  

R.G. Nath, H.-J.C. Chen, A. Nishikawa, R. Young-Sciame, and F.-L. Chung

A ³²P-postlabeling method for simultaneous detection and quantification of exocyclic etheno and propano adducts in DNA
Carcinogenesis 1994 15: 979-984; doi:10.1093/carcin/15.5.979 [Abstract] [PDF] [Request Permissions]  

Roland C. Grafström, Jeannette M. Dypbukt, Kristina Sundqvist, Luigi Atzori, Inge Nielsen, Rodger D. Curren, and Curtis C. Harris

Pathobiological effects of acetaldehyde in cultured human epithelial cells and fibroblasts
Carcinogenesis 1994 15: 985-990; doi:10.1093/carcin/15.5.985 [Abstract] [PDF] [Request Permissions]  

Alok Sarkar, Biswajit Mukherjee, and Malay Chatterjee

Inhibitory effect of ß-carotene on chronic 2-acetylaminofluorene induced hepatocarcinogenesis in rat: reflection in hepatic drug metabolism
Carcinogenesis 1994 15: 1055-1060; doi:10.1093/carcin/15.5.1055 [Abstract] [PDF] [Request Permissions]  

E. Richter and A.R. Tricker

Nicotine inhibits the metabolic activation of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in rats
Carcinogenesis 1994 15: 1061-1064; doi:10.1093/carcin/15.5.1061 [Abstract] [PDF] [Request Permissions]  

Andrew C. Beach and Ramesh C. Gupta

DNA adducts of the ubiquitous enviromnental contaminant cyclopenta[cd]pyrene
Carcinogenesis 1994 15: 1065-1072; doi:10.1093/carcin/15.5.1065 [Abstract] [PDF] [Request Permissions]  

SHORT COMMUNICATION:

Jan J.P. Bogaards, Hans Verhagen, Marianne I. Willems, Geert van Poppel, and Peter J.van Bladeren

Consumption of Brussels sprouts results in elevated -class glutathione S-transferase levels in human blood plasma
Carcinogenesis 1994 15: 1073-1075; doi:10.1093/carcin/15.5.1073 [Abstract] [PDF] [Request Permissions]  

Henry J. Lin, Chun-Ya Han, David A. Bernstein, Warren Hsiao, Bruce K. Lin, and Steven Hardy

Ethnic distribution of the glutathione transferase Mu 1-1 (GSTM1) null genotype in 1473 individuals and application to bladder cancer susceptibifity
Carcinogenesis 1994 15: 1077-1081; doi:10.1093/carcin/15.5.1077 [Abstract] [PDF] [Request Permissions]  

Theodora R. Devereux, Catherine M. White, Robert C. Sills, John R. Bucher, Robert R. Maronpot, and Marshall W. Anderson

Low frequency of H-ras mutations in hepatocellular adenomas and carcinomas and in hepatoblastomas from B6C3F1 mice exposed to oxazepam in the diet
Carcinogenesis 1994 15: 1083-1087; doi:10.1093/carcin/15.5.1083 [Abstract] [PDF] [Request Permissions]  

Joy A. Alcedo, Manoj Misra, Joshua W. Hamilton, and Karen E. Wetterhahn

The genotoxic carcinogen chromium(VI) alters the metal-inducible expression but not the basal expression of the metailothionein gene in vivo
Carcinogenesis 1994 15: 1089-1092; doi:10.1093/carcin/15.5.1089 [Abstract] [PDF] [Request Permissions]  

David H. Sorscher and Marila Cordeiro-Stone

Inhibition of reporter gene expression in mammalian cells. Effects of distinct carcinogen lesions in DNA
Carcinogenesis 1994 15: 1093-1096; doi:10.1093/carcin/15.5.1093 [Abstract] [PDF] [Request Permissions]  

M.M. King, A. Hollingsworth, J. Cuzick, and R.C. Garner

The detection of adducts in human cervix tissue DNA using ³² P-postlabelling: a study of the relationship with smoking history and oral contraceptive use
Carcinogenesis 1994 15: 1097-1100; doi:10.1093/carcin/15.5.1097 [Abstract] [PDF] [Request Permissions]  

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