Carcinogenesis

POINTS OF VIEW:

The Editors

Is butadiene carcinogenic to humans?
Carcinogenesis 1995 16: 155; doi:10.1093/carcin/16.2.155 [PDF] [Request Permissions]  

Ronald L. Melnick and Michael C. Kohn

Mechanistic data indicate that 1,3-butadiene is a human carcinogen
Carcinogenesis 1995 16: 157-163; doi:10.1093/carcin/16.2.157 [Abstract] [PDF] [Request Permissions]  

James A. Bond, Leslie Recio, and Dragana Andjelkovich

Epidemiological and mechanistic data suggest that 1, 3-butadiene will not be carcinogenic to humans at exposures likely to be encountered in the environment or workplace
Carcinogenesis 1995 16: 165-171; doi:10.1093/carcin/16.2.165 [Abstract] [PDF] [Request Permissions]  

COMMENTARY:

June K. Dunnick, Michael R. Elwell, James Huff, and J.Carl Barrett

Chemically induced mammary gland cancer in the National Toxicology Program's carcinogenesis bioassay
Carcinogenesis 1995 16: 173-179; doi:10.1093/carcin/16.2.173 [Abstract] [PDF] [Request Permissions]  

ACCELERATED PAPER:

Marie H. Hanigan

Expression of gamma-glutamyl transpeptidase provides tumor cells with a selective growth advantage at physiologic concentrations of cyst(e)ine
Carcinogenesis 1995 16: 181-185; doi:10.1093/carcin/16.2.181 [Abstract] [PDF] [Request Permissions]  

ORIGINAL PAPERS:

Chau-Jong Wang, Miao-Jane Lee, Ming-Cheng Chang, and Jen-Kun Lin

Inhibition of tumor promotion in benzo[a]pyrene-initiated CD-1 mouse skin by crocetin
Carcinogenesis 1995 16: 187-191; doi:10.1093/carcin/16.2.187 [Abstract] [PDF] [Request Permissions]  

Deborah A. Trott, Andrew P. Cuthbert, Robert W. Overell, Ivana Russo, and Robert F. Newbold

Mechanisms involved in the immortalization of mammalian cells by ionizing radiation and chemical carcinogens
Carcinogenesis 1995 16: 193-204; doi:10.1093/carcin/16.2.193 [Abstract] [PDF] [Request Permissions]  

Amit H. Trivedi, Shambhu K. Roy, Rashmi K. Patel, Siddharth G. Adhvaryu, and Damodar B. Balar

Urine of tobaccolareca nut chewers causes genomic damage in Chinese hamster ovary cells
Carcinogenesis 1995 16: 205-208; doi:10.1093/carcin/16.2.205 [Abstract] [PDF] [Request Permissions]  

P. Ryden and J.A. Robertson

The effect of fibre source and fermentation on the apparent hydrophobic binding properties of wheat bran preparations for the mutagen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)
Carcinogenesis 1995 16: 209-216; doi:10.1093/carcin/16.2.209 [Abstract] [PDF] [Request Permissions]  

Masao Hirose, Keisuke Akagi, Ryohei Hasegawa, Makoto Yaono, Toshio Satoh, Yukihiko Hara, Keiji Wakabayashi, and Nobuyuki Ito

Chemoprevention of 2-amino-1-methyl-6-phenylimidazo[4, 5-b]-pyridine (PhIP)-induced mammary gland carcinogenesis by antioxidants in F344 female rats
Carcinogenesis 1995 16: 217-221; doi:10.1093/carcin/16.2.217 [Abstract] [PDF] [Request Permissions]  

Michael Fenech and Josephine Rinaldi

A comparison of lymphocyte micronuclei and plasma micronutrients in vegetarians and non-vegetarians
Carcinogenesis 1995 16: 223-230; doi:10.1093/carcin/16.2.223 [Abstract] [PDF] [Request Permissions]  

Agneta Blanck, DeZhong Liao, Jan-Åke Gustafsson, and Inger Porsch Hällström

Hormonal regulation of sex differentiated parameters in liver nodules from rats treated in the resistant hepatocyte model
Carcinogenesis 1995 16: 231-235; doi:10.1093/carcin/16.2.231 [Abstract] [PDF] [Request Permissions]  

Halima Bessi, Claudine Rast, Benoit Rether, Giao Nguyen-Ba, and Paule Vasseur

Synergistic effects of chlordane and TPA in multistage morphological transformation of SHE cells
Carcinogenesis 1995 16: 237-244; doi:10.1093/carcin/16.2.237 [Abstract] [PDF] [Request Permissions]  

Laurent Baricault, Gerard Denariaz, Jean-Jacques Houri, Christine Bouley, Catherine Sapin, and Germain Trugnan

Use of HT-29, a cultured human colon cancer cell line, to study the effect of fermented milks on colon cancer cell growth and differentiation
Carcinogenesis 1995 16: 245-252; doi:10.1093/carcin/16.2.245 [Abstract] [PDF] [Request Permissions]  

Shuichi Adachi, Magnus Zeisig, and Lennart Möller

Improvements in the analytical method for 8-hydroxydeoxyguanosine in nuclear DNA
Carcinogenesis 1995 16: 253-258; doi:10.1093/carcin/16.2.253 [Abstract] [PDF] [Request Permissions]  

Joseph C. Siglin, Leena Khare, and Gary D. Stoner

Evaluation of dose and treatment duration on the esophageal tumorigenicity of N-nitrosomethylbenzylamine in rats
Carcinogenesis 1995 16: 259-265; doi:10.1093/carcin/16.2.259 [Abstract] [PDF] [Request Permissions]  

Cynthia R. Giver, Stephen L. Nelson, Jr, Mirabelle Y. Cha, Punnajit Pongsaensook, and Andrew J. Grosovsky

Mutational spectrum of X-ray induced TK^– human cell mutants
Carcinogenesis 1995 16: 267-275; doi:10.1093/carcin/16.2.267 [Abstract] [PDF] [Request Permissions]  

Gulzar Wani and Steven M.D' Ambrosio

Cell type-specific expression of human 8-oxo-7,8-dihydroguanosine triphosphatase in normal breast and skin tissues in vivo
Carcinogenesis 1995 16: 277-283; doi:10.1093/carcin/16.2.277 [Abstract] [PDF] [Request Permissions]  

R.D. Storer, M.E. Cartwright, W.O. Cook, K.A. Soper, and W.W. Nichols

Short-term carcinogenesis bioassay of genotoxic procarcinogens in PIM^® transgenic mice
Carcinogenesis 1995 16: 285-293; doi:10.1093/carcin/16.2.285 [Abstract] [PDF] [Request Permissions]  

James F. Hatcher and Santhanam Swaminathan

Detection of deoxyadenosine-4-aminobiphenyl adduct in DNA of human uroepithelial cells treated with N-hydroxy-4-aminobiphenyl following nuclease P1 enrichment and ³²P-postlabeling analysis
Carcinogenesis 1995 16: 295-301; doi:10.1093/carcin/16.2.295 [Abstract] [PDF] [Request Permissions]  

Alexander A. Constan, Raymond S.H. Yang, Dale C. Baker, and Stephen A. Benjamin

A unique pattern of hepatocyte proliferation in F344 rats following long-term exposures to low levels of a chemical mixture of groundwater contaminants
Carcinogenesis 1995 16: 303-310; doi:10.1093/carcin/16.2.303 [Abstract] [PDF] [Request Permissions]  

Yuh-Shan Jou, Beth Layhe, Diane F. Matesic, Chia-Cheng Chang, Adriaan W.de Feijter, Lizbeth Lockwood, Clifford W. Welsch, James E. Klaunig, and James E. Trosko

Inhibition of gap junctional intercellular communication and malignant transformation of rat liver epithelial cells by neu oncogene
Carcinogenesis 1995 16: 311-317; doi:10.1093/carcin/16.2.311 [Abstract] [PDF] [Request Permissions]  

Jeanne A. Hardy and Ann E. Aust

The effect of iron binding on the ability of crocidolite asbestos to catalyze DNA single-strand breaks
Carcinogenesis 1995 16: 319-325; doi:10.1093/carcin/16.2.319 [Abstract] [PDF] [Request Permissions]  

Kerry-Ann da Costa, Sanford C. Garner, Jerjang Chang, and Steven H. Zeisel

Effects of prolonged (1 year) choline deficiency and subsequent re-feeding of choline on 1,2-sn-diradylglycerol, fatty acids and protein kinase C in rat liver
Carcinogenesis 1995 16: 327-334; doi:10.1093/carcin/16.2.327 [Abstract] [PDF] [Request Permissions]  

Daniel Ballmaier and Bernd Epe

Oxidative DNA damage induced by potassium bromate under cell-free conditions and in mammalian cells
Carcinogenesis 1995 16: 335-342; doi:10.1093/carcin/16.2.335 [Abstract] [PDF] [Request Permissions]  

Samuel M. Cohen, Martin Cano, Emily M. Garland, Margaret St John, and Lora L. Arnold

Urinary and urothelial effects of sodium salts in male rats
Carcinogenesis 1995 16: 343-348; doi:10.1093/carcin/16.2.343 [Abstract] [PDF] [Request Permissions]  

Yusuke Hiraku, Sumiko Inoue, Shinji Oikawa, Koji Yamamoto, Saeko Tada, Kohsuke Nishino, and Shosuke Kawanishi

Metal-mediated oxidative damage to cellular and isolated DNA by certain tryptophan metabolites
Carcinogenesis 1995 16: 349-356; doi:10.1093/carcin/16.2.349 [Abstract] [PDF] [Request Permissions]  

Bing Mao, Jing Xu, Bin Li, Leonid A. Margulis, Sergey Smirnov, Nai-Qi Ya, Scott H. Courtney, and Nicholas E. Geacintov

Synthesis and characterization of covalent adducts derived from the binding of benzo[a]pyrene diol epoxide to a -GGG- sequence in a deoxyoligonucleotide
Carcinogenesis 1995 16: 357-365; doi:10.1093/carcin/16.2.357 [Abstract] [PDF] [Request Permissions]  

Christopher E. Frantz, Christy Bangerter, Ester Fultz, Kathryn M. Mayer, John S. Vogel, and Kenneth W. Turteltaub

Dose-response studies of MeIQx in rat liver and liver DNA at low doses
Carcinogenesis 1995 16: 367-373; doi:10.1093/carcin/16.2.367 [Abstract] [PDF] [Request Permissions]  

Chee K. Choo, Ellen A. Rorke, and Richard L. Eckert

Retinoid regulation of cell differentiation in a series of human papillomavirus type 16-immortalized human cervical epithelial cell lines
Carcinogenesis 1995 16: 375-381; doi:10.1093/carcin/16.2.375 [Abstract] [PDF] [Request Permissions]  

Paul D. Boucher and Ronald N. Hines

In vitro binding and functional studies comparing the human CYPIAI negative regulatory element with the orthologous sequences from rodent genes
Carcinogenesis 1995 16: 383-392; doi:10.1093/carcin/16.2.383 [Abstract] [PDF] [Request Permissions]  

I. Berberian, L.-C. Chen, F. R. Robinson, H. P. Glauert, C. K. Chow, and L. W. Robertson

Effect of dietary retinyl palmitate on the promotion of altered hepatic foci by 3,3',4,4'-tetrachlorobiphenyl and 2,2',4,4',5,5'- hexachiorobiphenyl in rats initiated with diethylnitrosamine
Carcinogenesis 1995 16: 393-398; doi:10.1093/carcin/16.2.393 [Abstract] [PDF] [Request Permissions]  

Rajendra G. Mehta, Jinfang Liu, Andreas Constantinou, Cathy F. Thomas, Michael Hawthorne, Min You, Clarissa Gerhäuser, John M. Pezzuto, Richard C. Moon, and Robert M. Moriarty

Cancer chemopreventive activity of brassinin, a phytoalexin from cabbage
Carcinogenesis 1995 16: 399-404; doi:10.1093/carcin/16.2.399 [Abstract] [PDF] [Request Permissions]  

R. Roy, S. Shiota, S.J. Kennel, R. Raha, M.von Wronski, T.P. Brent, and S. Mitra

A comparative study of the biochemical properties of human and mouse recombinant O⁶-methylguanine-DNA methyltransferases
Carcinogenesis 1995 16: 405-411; doi:10.1093/carcin/16.2.405 [Abstract] [PDF] [Request Permissions]  

H.-C. Chou, N. P. Lang, and F. F. Kadlubar

Metabolic activation of the N-hydroxy derivative of the carcinogen 4-aminobiphenyl by human tissue sulfotransferases
Carcinogenesis 1995 16: 413-417; doi:10.1093/carcin/16.2.413 [Abstract] [PDF] [Request Permissions]  

SHORT COMMUNICATION:

Han-Ming Shen, Choon-Nam Ong, Bee-Lan Lee, and Chen-Yang Shi

Aflatoxin B₁-induced 8-hydroxydeoxyguanosine formation in rat hepatic DNA
Carcinogenesis 1995 16: 419-422; doi:10.1093/carcin/16.2.419 [Abstract] [PDF] [Request Permissions]  

Johannes Corley, Robert J. Hurtubise, Elise D. Bowman, and Ainsley Weston

Solid matrix, room temperature phosphorescence identification and quantitation of the tetrahydrotetrols derived from the acid hydrolysis of benzo[a]pyrene - DNA adducts from human lung
Carcinogenesis 1995 16: 423-426; doi:10.1093/carcin/16.2.423 [Abstract] [PDF] [Request Permissions]  

R. M. Pascale, M. M. Simile, M. R. De Miglio, A. Nufris, L. Daino, M. A. Seddaiu, P. M. Rao, S. Rajalakshmi, D. S. R. Sarma, and F. Feo

Chemoprevention by S-adenosyl-L-methionine of rat liver carcinogenesis initiated by 1,2-dimethylhydrazine and promoted by orotic acid
Carcinogenesis 1995 16: 427-430; doi:10.1093/carcin/16.2.427 [Abstract] [PDF] [Request Permissions]  

Karam El-Bayoumy, Young-Heum Chae, Pramod Upadhyaya, Abraham Rivenson, Christine Kurtzke, Bandaru Reddy, and Stephen S. Hecht

Comparative tumorigenicity of benzo[a]pyrene, 1-nitropyrene and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine administered by gavage to female CD rats
Carcinogenesis 1995 16: 431-434; doi:10.1093/carcin/16.2.431 [Abstract] [PDF] [Request Permissions]  

Author index:

Author index
Carcinogenesis 1995 16: 435; doi:10.1093/carcin/16.2.435 [PDF] [Request Permissions]  

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