Carcinogenesis

COMMENTARY:

Edward L. Loechler

The role of adduct site-specific mutagenesis in understanding how carcinogen-DNA adducts cause mutations: perspective, prospects and problems
Carcinogenesis 1996 17: 895-902; doi:10.1093/carcin/17.5.895 [Abstract] [PDF] [Request Permissions]  

ACCELERATED PAPERS:

Meike Mevissen, Alexander Lerchl, Marta Szamel, and Wolfgang Löscher

Exposure of DMBA-treated female rats in a 50-Hz, 50 µTesla magnetic field: effects on mammary tumor growth, melatonin levels, and T lymphocyte activation
Carcinogenesis 1996 17: 903-910; doi:10.1093/carcin/17.5.903 [Abstract] [PDF] [Request Permissions]  

Giuseppe Curigliano, Yu-Jing Zhang, Li-Yu Wang, Giovanna Flamini, Antonio Alcini, Carlo Ratto, Mario Giustacchini, Eugenio Alcini, Achille Cittadini, and Regina M. Santella

Immunohistochemical quantitation of 4-aminobiphenyl-DNA adducts and p53 nuclear overexpression in T1 bladder cancer of smokers and nonsmokers
Carcinogenesis 1996 17: 911-916; doi:10.1093/carcin/17.5.911 [Abstract] [PDF] [Request Permissions]  

Udaya-sankar Devanaboyina and Ramesh C. Gupta

Sensitive detection of 8-hydroxy-2'-deoxyguanosine in DNA by ³²P-postlabeling assay and the basal levels in rat tissues
Carcinogenesis 1996 17: 917-924; doi:10.1093/carcin/17.5.917 [Abstract] [PDF] [Request Permissions]  

Judy L. Bolton and Li Shen

p-Quinone methides are the major decomposition products of catechol estrogen o-quinones
Carcinogenesis 1996 17: 925-929; doi:10.1093/carcin/17.5.925 [Abstract] [PDF] [Request Permissions]  

ORIGINAL ARTICLES:

Zongyi Hu, Ritva P. Evarts, Kozo Fujio, Nobuhiko Omori, Masako Omori, Elizabeth R. Marsden, and Snorri S. Thorgeirsson

CANCER BIOLOGY: Expression of transforming growth factor alpha/epidermal growth factor receptor, hepatocyte growth factor/c-met and acidic fibroblast growth factor/fibroblast growth factor receptors during hepatocarcinogenesis
Carcinogenesis 1996 17: 931-938; doi:10.1093/carcin/17.5.931 [Abstract] [PDF] [Request Permissions]  

Elena L. Paley

CANCER BIOLOGY: Phosphorylation of T antigen and p53 in carcinogen-treated SV40-transformed Chinese hamster cells
Carcinogenesis 1996 17: 939-945; doi:10.1093/carcin/17.5.939 [Abstract] [PDF] [Request Permissions]  

Kyle L. Kolaya, Donald E. Stevenson, Earl F. Walborg, Jr, and James E. Klaunig

CANCER BIOLOGY: Dose dependence of phenobarbital promotion of preneoplastic hepatic lesions in F344 rats and B6C3F1 mice: effects on DNA synthesis and apoptosis
Carcinogenesis 1996 17: 947-954; doi:10.1093/carcin/17.5.947 [Abstract] [PDF] [Request Permissions]  

M.St J. Battalora, C.J. Conti, C.M. Aldaz, T.J. Slaga, D.A. Johnston, and J. DiGiovanni

CANCER BIOLOGY: Regression and progression characteristics of papillomas induced by chrysarobin in SENCAR mice
Carcinogenesis 1996 17: 955-960; doi:10.1093/carcin/17.5.955 [Abstract] [PDF] [Request Permissions]  

Kumiko Ogawa, Tung-Tien Sun, and Samuel M. Cohen

CANCER BIOLOGY: Analysis of differentiation-associated proteins in rat bladder carcinogenesis
Carcinogenesis 1996 17: 961-965; doi:10.1093/carcin/17.5.961 [Abstract] [PDF] [Request Permissions]  

Duncan T. Ho and Michel Roberge

CANCER BIOLOGY: The antitumor drug fostriecin induces vimentin hyperphosphorylation and intermediate filament reorganization
Carcinogenesis 1996 17: 967-972; doi:10.1093/carcin/17.5.967 [Abstract] [PDF] [Request Permissions]  

T.C. Orton, S.E. Doughty, A.E. Kalinowski, P.G. Lord, and P.F. Wadsworth

CANCER BIOLOGY: Expression of growth factors and growth factor receptors in the liver of C57BL/10J mice following administration of phenobarbitone
Carcinogenesis 1996 17: 973-981; doi:10.1093/carcin/17.5.973 [Abstract] [PDF] [Request Permissions]  

Mohammed H. Moghadasian, Hugh J. Freeman, and David V. Godin

CANCER BIOLOGY: Endogenous antioxidant status in neoplastic and adjacent tissues in 1,2-dimethylhydrazine-induced colon cancer in rats: effects of olsalazine
Carcinogenesis 1996 17: 983-987; doi:10.1093/carcin/17.5.983 [Abstract] [PDF] [Request Permissions]  

Michele P. Winesett, Ginger W. Ramsey, and John A. Barnard

CANCER BIOLOGY: Type II TGFß receptor expression in intestinal cell lines and in the intestinal tract
Carcinogenesis 1996 17: 989-995; doi:10.1093/carcin/17.5.989 [Abstract] [PDF] [Request Permissions]  

Robert J. Isfort, Gary A. Kerckaert, David B. Cody, Janet Carter, Kevin E. Driscoll, and Robert A. LeBoeuf

CANCER BIOLOGY: Isolation and biological characterization of morphological transformation-sensitive Syrian hamster embryo cells
Carcinogenesis 1996 17: 997-1005; doi:10.1093/carcin/17.5.997 [Abstract] [PDF] [Request Permissions]  

MOLECULAR EPIDEMIOLOGY AND CANCER PREVENTION:

Y. Soini, S.C. Chia, W.P. Bennett, J.D. Groopman, J.-S. Wang, V.M.G. DeBenedetti, H. Cawley, J-A. Welsh, C. Hansen, N.V. Bergasa, E. A Jones, A.M. DiBisceglie, G.E. Trivers, C.A. Sandoval, I.E. Calderon, L.E.Munoz Espinosa, and C.C. Harris

An aflatoxin-associated mutational hotspot at codon 249 in the p53 tumor suppressor gene occurs in hepatocellular carcinomas from Mexico
Carcinogenesis 1996 17: 1007-1012; doi:10.1093/carcin/17.5.1007 [Abstract] [PDF] [Request Permissions]  

James C. Fuscoe, R.Woodrow Setzer, Deborah D. Collard, and Martha M. Moore

Quantification of t(14;18) in the lymphocytes of healthy adult humans as a possible biomarker for environmental exposures to carcinogens
Carcinogenesis 1996 17: 1013-1020; doi:10.1093/carcin/17.5.1013 [Abstract] [PDF] [Request Permissions]  

Per Sabro Nielsen, Nettie de Pater, Henrik Okkels, and Herman Autrup

Environmental air pollution and DNA adducts in Copenhagen bus drivers—Effect of GSTM1 and NAT2 genotypes on adduct levels
Carcinogenesis 1996 17: 1021-1027; doi:10.1093/carcin/17.5.1021 [Abstract] [PDF] [Request Permissions]  

Yukari Totsuka, Kazuo Fukutome, Mami Takahashi, Satoru Takahashi, Akihiro Tada, Takashi Sugimura, and Keiji Wakabayashi

Presence of N²-(deoxyguanosin-8-yl)-2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (dG-C8-MeIQx) in human tissues
Carcinogenesis 1996 17: 1029-1034; doi:10.1093/carcin/17.5.1029 [Abstract] [PDF] [Request Permissions]  

Jia-Long Fang, Carlos E. Vaca, Liisa M. Valsta, and Marja Mutanen

Determination of DNA adducts of malonaldehyde in humans: effects of dietary fatty acid composition
Carcinogenesis 1996 17: 1035-1040; doi:10.1093/carcin/17.5.1035 [Abstract] [PDF] [Request Permissions]  

Shunso Hatono, Arnie Jimenez, and Michael J. Wargovich

Chemopreventive effect of S-allylcysteine and its relationship to the detoxification enzyme glutathione S-transferase
Carcinogenesis 1996 17: 1041-1044; doi:10.1093/carcin/17.5.1041 [Abstract] [PDF] [Request Permissions]  

Clement Ip, Stephanie P. Briggs, Albert D. Haegele, Henry J. Thompson, Jayne Storkson, and Joseph A. Scimeca

The efficacy of conjugated linoleic acid in mammary cancer prevention is independent of the level or type of fat in the diet
Carcinogenesis 1996 17: 1045-1050; doi:10.1093/carcin/17.5.1045 [Abstract] [PDF] [Request Permissions]  

CARCINOGENESIS:

L.M. Sargent, Y.P. Dragan, C. Sattler, N. Bahnub, G. Sattler, P. Martin, A. Cisneros, J. Mann, S. Thorgeirsson, V.C. Jordan, and H.C. Pitot

Induction of hepatic aneuploidy in vivo by tamoxifen, toremifene and idoxifene in female Sprague-Dawley rats
Carcinogenesis 1996 17: 1051-1056; doi:10.1093/carcin/17.5.1051 [Abstract] [PDF] [Request Permissions]  

Marjorie Romkes, Herng-Der Chem, Timothy G. Lesnick, Michael J. Becich, Raj Persad, Patrick Smith, and Robert A. Branch

Association of low CYP3A activity with p53 mutation and CYP2D6 activity with Rb mutation in human bladder cancer
Carcinogenesis 1996 17: 1057-1062; doi:10.1093/carcin/17.5.1057 [Abstract] [PDF] [Request Permissions]  

Gregory A. Reed and Brian C. Jones

Enhancement of benzo[a]pyrene diol epoxide mutagenicity by sulfite in a mammalian test system
Carcinogenesis 1996 17: 1063-1068; doi:10.1093/carcin/17.5.1063 [Abstract] [PDF] [Request Permissions]  

E.H. Vock, H.-G. Hoymann, U. Heinrich, and W.K. Lutz

³²P-Postlabeling of a DNA adduct derived from 4,4'-methylenedianiline, in the olfactory epithelium of rats exposed by inhalation to 4,4'-methylenediphenyl diisocyanate
Carcinogenesis 1996 17: 1069-1073; doi:10.1093/carcin/17.5.1069 [Abstract] [PDF] [Request Permissions]  

Soisungwan Satarug, Melissa R. Haswell-Elkins, Mitsuhiro Tsuda, Pisaln Mairiang, Paiboon Sithithaworn, Eimorn Mairiang, Hiroyasu Esumi, Saowalak Sukprasert, Puangrat Yongvanit, and David B. Elkins

Thiocyanate-independent nitrosation in humans with carcinogenic parasite infection
Carcinogenesis 1996 17: 1075-1081; doi:10.1093/carcin/17.5.1075 [Abstract] [PDF] [Request Permissions]  

L.A.P. Ballering, M.J.M. Nivard, and E.W. Vogel

Characterization by two-endpoint comparisons of the genetic toxicity profiles of vinyl chloride and related etheno-adduct forming carcinogens in Drosophila
Carcinogenesis 1996 17: 1083-1092; doi:10.1093/carcin/17.5.1083 [Abstract] [PDF] [Request Permissions]  

J. Schulze, W. Schläger, R. Wilnsch, and E. Richter

Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by hamster, mouse and rat intestine: relevance of species differences
Carcinogenesis 1996 17: 1093-1099; doi:10.1093/carcin/17.5.1093 [Abstract] [PDF] [Request Permissions]  

Carole Lerche, Catherine Le Jossic, Alain Fautrel, Isabelle de Waziers, François Ballet, Andre Guillouzo, and Laurent Corcos

Rat liver epithelial cells express functional cytochrome P450 2E1
Carcinogenesis 1996 17: 1101-1106; doi:10.1093/carcin/17.5.1101 [Abstract] [PDF] [Request Permissions]  

Girija Kuttan, Lata G. Menon, and Ramadasan Kuttan

Prevention of 20-methylcholanthrene-induced sarcoma by a mistletoe extract, Iscador
Carcinogenesis 1996 17: 1107-1109; doi:10.1093/carcin/17.5.1107 [Abstract] [PDF] [Request Permissions]  

Solfrid H. Nyholm, Jan Alexander, Elsa Lundanes, Henrik Frandsen, Rolf Andersson, Spiros Grivas, Stephen Nesnow, and JØrn A. Holme

Biotransformation of the cyclopenta-fused polycyclic aromatic hydrocarbon benz[j]aceanthrylene in isolated rat liver cells: identification of nine new metabolites
Carcinogenesis 1996 17: 1111-1120; doi:10.1093/carcin/17.5.1111 [Abstract] [PDF] [Request Permissions]  

Susan J. Land, Richard F. Jones, and Charles M. King

Genetic analysis of two rat acetyltransferases
Carcinogenesis 1996 17: 1121-1126; doi:10.1093/carcin/17.5.1121 [Abstract] [PDF] [Request Permissions]  

Lance Encell, Peter G. Foiles, and Barry Gold

The relationship between N-nitrosodimethylamine metabolism and DNA methylation in isolated rat hepatocytes
Carcinogenesis 1996 17: 1127-1134; doi:10.1093/carcin/17.5.1127 [Abstract] [PDF] [Request Permissions]  

Joseph C. Siglin, Mark A. Morse, Herman A. J. Schut, Robert G. Geil, Philip B. Conran, and Gary D. Stoner

O⁶-Methyguanine levels and histopathological changes in the rat esophagus and liver following single and repeated administration of N-nitrosomethylbenzylamin
Carcinogenesis 1996 17: 1135-1140; doi:10.1093/carcin/17.5.1135 [Abstract] [PDF] [Request Permissions]  

Xiao Mei Gao, Elisabeth M. Perchellet, Amy W. Davis, Steven W. Newell, Duy H. Hua, and Jean-Pierre Perchellet

Characterization of the antitumor-promoting activity of camptothecin in SENCAR mouse skin
Carcinogenesis 1996 17: 1141-1148; doi:10.1093/carcin/17.5.1141 [Abstract] [PDF] [Request Permissions]  

SHORT COMMUNICATIONS:

David H. Phillips, Alan Hewer, Philip L. Grover, Grace K. Poon, and Paul L. Carmichael

Tamoxifen does not form detectable DNA adducts in white blood cells of breast cancer patients
Carcinogenesis 1996 17: 1149-1152; doi:10.1093/carcin/17.5.1149 [Abstract] [PDF] [Request Permissions]  

Antonietta Martelli, Francesca Mattioli, Marco Ghia, Eugenio Mereto, and Giovanni Brambilla

Comparative study of DNA repair induced by cyproterone acetate, chlormadinone acetate and megestrol acetate in primary cultures of human and rat hepatocytes
Carcinogenesis 1996 17: 1153-1156; doi:10.1093/carcin/17.5.1153 [Abstract] [PDF] [Request Permissions]  

Valérie Lecureur, André Guillouzo, and Olivier Fardel

Differential regulation of mdr genes in response to 2-acetylaminofluorene treatment in cultured rat and human hepatocytes
Carcinogenesis 1996 17: 1157-1160; doi:10.1093/carcin/17.5.1157 [Abstract] [PDF] [Request Permissions]  

E.Maria Donner and R.Julian Preston

The relationship between p53 status, DNA repair and chromatid aberration induction in G₂ mouse embryo fibroblast cells treated with bleomycin
Carcinogenesis 1996 17: 1161-1165; doi:10.1093/carcin/17.5.1161 [Abstract] [PDF] [Request Permissions]  

Ajai K. Chaudhary, G.Ramachandra Reddy, Ian A. Blair, and Lawrence J. Marnett

Characterization of an N⁶-oxopropenyl-'-deoxyadenosine adduct in malondialdehyde-modified DNA using liquid chromatography/electrospry ionization tandem mass spectrometry
Carcinogenesis 1996 17: 1167-1170; doi:10.1093/carcin/17.5.1167 [Abstract] [PDF] [Request Permissions]  

Shabbir Moochhala, Vikram J.S. Chhatwal, Steven T.F. Chan, Sing Shang Ngoi, Yee Wen Chia, and Abu Rauff

Nitric oxide synthase activity and expression in human colorectal cancer
Carcinogenesis 1996 17: 1171-1174; doi:10.1093/carcin/17.5.1171 [Abstract] [PDF] [Request Permissions]  

Helen Enright, Wesley J. Miller, Rebecca Hays, Robert A. Floyd, and Robert P. Hebbel

Preferential targeting of oxidative base damage to interucleosomal DNA
Carcinogenesis 1996 17: 1175-1177; doi:10.1093/carcin/17.5.1175 [Abstract] [PDF] [Request Permissions]  

Juha M.T. Hyttinen, Sanna Myöhänen, and Kristian Jansson

Kinds of mutations induced by 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) in the hprt gene of Chinese hamster ovary cells
Carcinogenesis 1996 17: 1179-1181; doi:10.1093/carcin/17.5.1179 [Abstract] [PDF] [Request Permissions]  

Lucymara F. Agnez, Regina L.Costa de Oliveira, Paolo Di Mascio, and Carlos F.M. Menck

Involvement of Escherichia coli exonuclease III and endonuclease IV in the repair of singlet oxygen-induced DNA damage
Carcinogenesis 1996 17: 1183-1185; doi:10.1093/carcin/17.5.1183 [Abstract] [PDF] [Request Permissions]  

Author index:

Author index
Carcinogenesis 1996 17: 1186; doi:10.1093/carcin/17.5.1186 [PDF] [Request Permissions]  

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