Carcinogenesis

COMMENTARY:

Ian N.H. White

The tamoxifen dilemma
Carcinogenesis 1999 20: 1153-1160; doi:10.1093/carcin/20.7.1153 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

ACCELERATED PAPER:

Frank D. Hong, Jun Chen, Scott Donovan, Nancy Schneider, and Perry D. Nisen

Taxol, vincristine or nocodazole induces lethality in G₁-checkpoint-defective human astrocytoma U373MG cells by triggering hyperploid progression
Carcinogenesis 1999 20: 1161-1168; doi:10.1093/carcin/20.7.1161 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

CANCER BIOLOGY:

Geoffrey A. Wood, Dittakavi S.R. Sarma, and Michael C. Archer

Resistance to the promotion of glutathione S-transferase 7-7-positive liver lesions in Copenhagen rats
Carcinogenesis 1999 20: 1169-1175; doi:10.1093/carcin/20.7.1169 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ines Krueger, Leon H.F. Mullenders, and Andrea Hartwig

Nickel(II) increases the sensitivity of V79 Chinese hamster cells towards cisplatin and transplatin by interference with distinct steps of DNA repair
Carcinogenesis 1999 20: 1177-1184; doi:10.1093/carcin/20.7.1177 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Mukta M. Webber, Nicholas Trakul, Peter S. Thraves, Diana Bello-DeOcampo, William W. Chu, Patrick D. Storto, Thomas K. Huard, Johng S. Rhim, and Daniel E. Williams

A human prostatic stromal myofibroblast cell line WPMY-1: a model for stromal–epithelial interactions in prostatic neoplasia
Carcinogenesis 1999 20: 1185-1192; doi:10.1093/carcin/20.7.1185 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ricky Chang-Tze Yu, Te-Chang Lee, T.C. Wang, and Jih-Heng Li

Genetic toxicity of cocaine
Carcinogenesis 1999 20: 1193-1199; doi:10.1093/carcin/20.7.1193 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Chao Xing and Walter Imagawa

Altered MAP kinase (ERK1,2) regulation in primary cultures of mammary tumor cells: elevated basal activity and sustained response to EGF
Carcinogenesis 1999 20: 1201-1208; doi:10.1093/carcin/20.7.1201 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

S. Chevalier and R.A. Roberts

G₁-arrested FaO cells re-enter the cell cycle upon stimulation with the rodent non-genotoxic hepatocarcinogen nafenopin
Carcinogenesis 1999 20: 1209-1213; doi:10.1093/carcin/20.7.1209 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

MOLECULAR EPIDEMIOLOGY AND CANCER PREVENTION:

Laundette P. Knight, Thomas Primiano, John D. Groopman, Thomas W. Kensler, and Thomas R. Sutter

cDNA cloning, expression and activity of a second human aflatoxin B₁-metabolizing member of the aldo-keto reductase superfamily, AKR7A3
Carcinogenesis 1999 20: 1215-1223; doi:10.1093/carcin/20.7.1215 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

M.C. Lemos, F.J. Cabrita, H.A. Silva, M. Vivan, F. Plácido, and F.J. Regateiro

Genetic polymorphism of CYP2D6, GSTM1 and NAT2 and susceptibility to haematological neoplasias
Carcinogenesis 1999 20: 1225-1229; doi:10.1093/carcin/20.7.1225 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

L.E. Beckman, G.F. Van Landeghem, C. Sikström, A. Wahlin, B. Markevärn, G. Hallmans, P. Lenner, L. Athlin, R. Stenling, and L. Beckman

Interaction between haemochromatosis and transferrin receptor genes in different neoplastic disorders
Carcinogenesis 1999 20: 1231-1233; doi:10.1093/carcin/20.7.1231 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Annette Clairmont, Helmut Sies, Sudarshan Ramachandran, John T. Lear, Andrew G. Smith, Bill Bowers, Peter W. Jones, Anthony A. Fryer, and Richard C. Strange

Association of NAD(P)H:quinone oxidoreductase (NQO1) null with numbers of basal cell carcinomas: use of a multivariate model to rank the relative importance of this polymorphism and those at other relevant loci
Carcinogenesis 1999 20: 1235-1240; doi:10.1093/carcin/20.7.1235 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

CARCINOGENESIS:

Magnus Zeisig, Tim Hofer, Jean Cadet, and Lennart Möller

³²P-postlabeling high-performance liquid chromatography (³²P-HPLC) adapted for analysis of 8-hydroxy-2'-deoxyguanosine
Carcinogenesis 1999 20: 1241-1245; doi:10.1093/carcin/20.7.1241 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Emile M. Youssef, Hideki Wanibuchi, Satoru Mori, Elsayed I. Salim, Shuji Hayashi, and Shoji Fukushima

Elevation of urinary enzyme levels in rat bladder carcinogenesis
Carcinogenesis 1999 20: 1247-1252; doi:10.1093/carcin/20.7.1247 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Pertti Koivisto, Ilkka Kilpeläinen, Ilpo Rasanen, Ilse-Dore Adler, Francesca Pacchierotti, and Kimmo Peltonen

Butadiene diolepoxide- and diepoxybutane-derived DNA adducts at N7-guanine: a high occurrence of diolepoxide-derived adducts in mouse lung after 1,3-butadiene exposure
Carcinogenesis 1999 20: 1253-1259; doi:10.1093/carcin/20.7.1253 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Masashi Tokieda, Shoji Honda, Toshio Fujioka, and Masaru Nasu

Effect of Helicobacter pylori infection on the N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric carcinogenesis in Mongolian gerbils
Carcinogenesis 1999 20: 1261-1266; doi:10.1093/carcin/20.7.1261 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Jeu-Ming P. Yuann, Ke Jian Liu, Joshua W. Hamilton, and Karen E. Wetterhahn

In vivo effects of ascorbate and glutathione on the uptake of chromium, formation of chromium(V), chromium–DNA binding and 8-hydroxy-2'-deoxyguanosine in liver and kidney of Osteogenic Disorder Shionogi rats following treatment with chromium(VI)
Carcinogenesis 1999 20: 1267-1275; doi:10.1093/carcin/20.7.1267 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Jan Erik Paulsen, Inger-Lise Steffensen, Åshild Andreassen, Rose Vikse, and Jan Alexander

Neonatal exposure to the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine via breast milk or directly induces intestinal tumors in multiple intestinal neoplasia mice
Carcinogenesis 1999 20: 1277-1282; doi:10.1093/carcin/20.7.1277 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Keisuke S. Iwamoto, Shiho Fujii, Akihiko Kurata, Makoto Suzuki, Tohru Hayashi, Yuji Ohtsuki, Yuhei Okada, Michihiko Narita, Masanori Takahashi, Sadahiro Hosobe, Kenji Doishita, Toshiaki Manabe, Sakae Hata, Ichiro Murakami, Satoru Hata, Shinji Itoyama, Seiya Akatsuka, Nobuya Ohara, Keisuke Iwasaki, Hisamasa Akabane, Megumu Fujihara, Toshio Seyama, and Takesaburo Mori

p53 mutations in tumor and non-tumor tissues of Thorotrast recipients: a model for cellular selection during radiation carcinogenesis in the liver
Carcinogenesis 1999 20: 1283-1291; doi:10.1093/carcin/20.7.1283 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Simon E. Tobi, Dan D. Levy, Michael M. Seidman1, and Kenneth H. Kraemer1

Sequence-dependent mutations in a shuttle vector plasmid replicated in a mismatch repair deficient human cell line
Carcinogenesis 1999 20: 1293-1301; doi:10.1093/carcin/20.7.1293 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

S.G. Kim, A. Liem, B.C. Stewart, and J.A. Miller

New studies on trans-anethole oxide and trans-asarone oxide
Carcinogenesis 1999 20: 1303-1307; doi:10.1093/carcin/20.7.1303 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Meenakshi Venugopal, Andrew Callaway, and Elizabeth G. Snyderwine

2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) retards mammary gland involution in lactating Sprague–Dawley rats
Carcinogenesis 1999 20: 1309-1314; doi:10.1093/carcin/20.7.1309 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

B.S. Shane, J.G. deBoer, B.W. Glickman, and M.L. Cunningham

Oxazepam is mutagenic in vivo in Big Blue^® transgenic mice
Carcinogenesis 1999 20: 1315-1321; doi:10.1093/carcin/20.7.1315 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Katsumichi Iki, Masahiro Tsutsumi, Akira Kido, Hiroyuki Sakitani, Makoto Takahama, Masatoshi Yoshimoto, Masaaki Motoyama, Kunihiko Tatsumi, Tsukasa Tsunoda, and Yoichi Konishi

Expression of matrix metalloproteinase 2 (MMP-2), membrane-type 1 MMP and tissue inhibitor of metalloproteinase 2 and activation of proMMP-2 in pancreatic duct adenocarcinomas in hamsters treated with N-nitrosobis(2-oxopropyl)amine
Carcinogenesis 1999 20: 1323-1329; doi:10.1093/carcin/20.7.1323 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Òscar Miró, Josep R. Alonso, Diana Jarreta, Jordi Casademont, Álvaro Urbano-Márquez, and Francesc Cardellach

Smoking disturbs mitochondrial respiratory chain function and enhances lipid peroxidation on human circulating lymphocytes
Carcinogenesis 1999 20: 1331-1336; doi:10.1093/carcin/20.7.1331 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Byeongwoo Ahn, Beom Seok Han, Dae Joong Kim, and Hiroshi Ohshima

Immunohistochemical localization of inducible nitric oxide synthase and 3-nitrotyrosine in rat liver tumors induced by N-nitrosodiethylamine
Carcinogenesis 1999 20: 1337-1344; doi:10.1093/carcin/20.7.1337 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Detlef Schuler and Erwin Eder

Detection of 1,N²-propanodeoxyguanosine adducts of 2-hexenal in organs of Fischer 344 rats by a ³²P-post-labeling technique
Carcinogenesis 1999 20: 1345-1350; doi:10.1093/carcin/20.7.1345 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Reginald Davies, Timothy W. Gant, Lewis L. Smith, and Jerry A. Styles

Tamoxifen induces G:CT:A mutations in the cII gene in the liver of lambda/lacI transgenic rats but not at 5'-CpG-3' dinucleotide sequences as found in the lacI transgene
Carcinogenesis 1999 20: 1351-1356; doi:10.1093/carcin/20.7.1351 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Françoise Tombolan, Dominique Renault, Dominique Brault, Magali Guffroy, François Périn, and Véronique Thybaud

Effect of mitogenic or regenerative cell proliferation on lacz mutant frequency in the liver of Muta^TMMice treated with 5,9-dimethyldibenzo[c,g]carbazole
Carcinogenesis 1999 20: 1357-1362; doi:10.1093/carcin/20.7.1357 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

SHORT COMMUNICATIONS:

Manuela Gariboldi, Rosa Pascale, Giacomo Manenti, Maria R.De Miglio, Diego Calvisi, Angelo Carru, Tommaso A. Dragani, and Francesco Feo

Analysis of loss of heterozygosity in neoplastic nodules induced by diethylnitrosamine in the resistant BFF1 rat strain
Carcinogenesis 1999 20: 1363-1368; doi:10.1093/carcin/20.7.1363 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Elizabeth A. Hanna, Sandra Umhauer, Stacie L. Roshong, Marie P. Piechocki, Martha J. Fernstrom, James D. Fanning, and Randall J. Ruch

Gap junctional intercellular communication and connexin43 expression in human ovarian surface epithelial cells and ovarian carcinomas in vivo and in vitro
Carcinogenesis 1999 20: 1369-1373; doi:10.1093/carcin/20.7.1369 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Hanspeter Witschi, Imelda Espiritu, and Dale Uyeminami

Chemoprevention of tobacco smoke-induced lung tumors in A/J strain mice with dietary myo-inositol and dexamethasone
Carcinogenesis 1999 20: 1375-1378; doi:10.1093/carcin/20.7.1375 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Oliver Moennikes, Albrecht Buchmann, Thomas Ott, Klaus Willecke1, and Michael Schwarz2

The effect of connexin32 null mutation on hepatocarcinogenesis in different mouse strains
Carcinogenesis 1999 20: 1379-1382; doi:10.1093/carcin/20.7.1379 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

CORRIGENDUM:

Suppression of extracellular signals and cell proliferation by the black tea polyphenol, theaflavin-3,3'-digallate
Carcinogenesis 1999 20: 1383. [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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