Carcinogenesis

COMMENTARY:

Harald B. Steen

The origin of oncogenic mutations: where is the primary damage?
Carcinogenesis 2000 21: 1773-1776; doi:10.1093/carcin/21.10.1773 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

ACCELERATED PAPER:

Uddhav P.Kelavkar, Cynthia Cohen, Hideki Kamitani, Thomas E.Eling, and Kamal F.Badr

Concordant induction of 15-lipoxygenase-1 and mutant p53 expression in human prostate adenocarcinoma: correlation with Gleason staging
Carcinogenesis 2000 21: 1777-1787; doi:10.1093/carcin/21.10.1777 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

CANCER BIOLOGY:

Wan-Lin Yang and Harold Frucht

Cholinergic receptor up-regulates COX-2 expression and prostaglandin E₂ production in colon cancer cells
Carcinogenesis 2000 21: 1789-1793; doi:10.1093/carcin/21.10.1789 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Günter Speit, Claudia Dennog, Uta Eichhorn, Andreas Rothfuß, and Bernd Kaina

Induction of heme oxygenase-1 and adaptive protection against the induction of DNA damage after hyperbaric oxygen treatment
Carcinogenesis 2000 21: 1795-1799; doi:10.1093/carcin/21.10.1795 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ronald Sluyter and Gary M. Halliday

Enhanced tumor growth in UV-irradiated skin is associated with an influx of inflammatory cells into the epidermis
Carcinogenesis 2000 21: 1801-1807; doi:10.1093/carcin/21.10.1801 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

A. Jayasurya, B.H. Bay, W.M. Yap, N.G. Tan, and B.K.H. Tan

Proliferative potential in nasopharyngeal carcinoma: correlations with metallothionein expression and tissue zinc levels
Carcinogenesis 2000 21: 1809-1812; doi:10.1093/carcin/21.10.1809 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

MOLECULAR EPIDEMIOLOGY AND CANCER PREVENTION:

M.J. Lafuente, X. Casterad, M. Trias, C. Ascaso, R. Molina, A. Ballesta, S. Zheng, J.K. Wiencke, and A. Lafuente

NAD(P)H:quinone oxidoreductase-dependent risk for colorectal cancer and its association with the presence of K-ras mutations in tumors
Carcinogenesis 2000 21: 1813-1819; doi:10.1093/carcin/21.10.1813 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Sikandar G. Khan, E.Jeffrey Metter, Robert E. Tarone, Vilhelm A. Bohr, Lawrence Grossman, Mohammad Hedayati, Sherri J. Bale, Steffen Emmert, and Kenneth H. Kraemer

A new xeroderma pigmentosum group C poly(AT) insertion/deletion polymorphism
Carcinogenesis 2000 21: 1821-1825; doi:10.1093/carcin/21.10.1821 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

A.Graeme Shepherd, Margaret M. Manson, Helen W.L. Ball, and Lesley I. McLellan

Regulation of rat glutamate-cysteine ligase (-glutamylcysteine synthetase) subunits by chemopreventive agents and in aflatoxin B₁-induced preneoplasia
Carcinogenesis 2000 21: 1827-1834; doi:10.1093/carcin/21.10.1827 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Hiroshi Inano, Makoto Onoda, Naoshi Inafuku, Megumi Kubota, Yasuhiro Kamada, Toshihiko Osawa, Hisae Kobayashi, and Katsumi Wakabayashi

Potent preventive action of curcumin on radiation-induced initiation of mammary tumorigenesis in rats
Carcinogenesis 2000 21: 1835-1841; doi:10.1093/carcin/21.10.1835 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Akira Murakami, Yoshimasa Nakamura, Takuji Tanaka, Kyuichi Kawabata, Daisuke Takahashi, Koichi Koshimizu, and Hajime Ohigashi

Suppression by citrus auraptene of phorbol ester- and endotoxin-induced inflammatory responses: role of attenuation of leukocyte activation
Carcinogenesis 2000 21: 1843-1850; doi:10.1093/carcin/21.10.1843 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

CARCINOGENESIS:

David J. Boocock, James L. Maggs, Karen Brown, Ian N.H. White, and B.Kevin Park

Major inter-species differences in the rates of O-sulphonation and O-glucuronylation of -hydroxytamoxifen in vitro: a metabolic disparity protecting human liver from the formation of tamoxifen–DNA adducts
Carcinogenesis 2000 21: 1851-1858; doi:10.1093/carcin/21.10.1851 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

John P.H. Wijen, Madeleine J.M. Nivard, and Ekkehart W. Vogel

The in vivo genetic activity profile of the monofunctional nitrogen mustard 2-chloroethylamine differs drastically from its bifunctional counterpart mechlorethamine
Carcinogenesis 2000 21: 1859-1867; doi:10.1093/carcin/21.10.1859 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Alexandra Löw-Baselli, Wolfgang W. Huber, Monika Käfer, Krystyna Bukowska, Rolf Schulte-Hermann, and Bettina Grasl-Kraupp

Failure to demonstrate chemoprevention by the monoterpene perillyl alcohol during early rat hepatocarcinogenesis: a cautionary note
Carcinogenesis 2000 21: 1869-1877; doi:10.1093/carcin/21.10.1869 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Akiko Shiraishi, Kunihiko Sakumi, and Mutsuo Sekiguchi

Increased susceptibility to chemotherapeutic alkylating agents of mice deficient in DNA repair methyltransferase
Carcinogenesis 2000 21: 1879-1883; doi:10.1093/carcin/21.10.1879 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Masaaki Nomura, Wei-ya Ma, Nanyue Chen, Ann M. Bode, and Zigang Dong

Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced NF-B activation by tea polyphenols, (–)-epigallocatechin gallate and theaflavins
Carcinogenesis 2000 21: 1885-1890; doi:10.1093/carcin/21.10.1885 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Masami Yamamoto, Tetsuya Tsukamoto, Hiroki Sakai, Norimitsu Shirai, Hiroko Ohgaki, Chie Furihata, Lawrence A. Donehower, Kenji Yoshida, and Masae Tatematsu

p53 knockout mice (–/–) are more susceptible than (+/–) or (+/+) mice to N-methyl-N-nitrosourea stomach carcinogenesis
Carcinogenesis 2000 21: 1891-1897; doi:10.1093/carcin/21.10.1891 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Yoshimasa Nakamura, Koji Torikai, Yoshimi Ohto, Akira Murakami, Takuji Tanaka, and Hajime Ohigashi

A simple phenolic antioxidant protocatechuic acid enhances tumor promotion and oxidative stress in female ICR mouse skin: dose- and timing-dependent enhancement and involvement of bioactivation by tyrosinase
Carcinogenesis 2000 21: 1899-1907; doi:10.1093/carcin/21.10.1899 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Aloys L.A. Sesink, Denise S.M.L. Termont, Jan H. Kleibeuker, and Roelof Van der Meer

Red meat and colon cancer: dietary haem, but not fat, has cytotoxic and hyperproliferative effects on rat colonic epithelium
Carcinogenesis 2000 21: 1909-1915; doi:10.1093/carcin/21.10.1909 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Todd A. Thompson, Jill D. Haag, and Michael N. Gould

ras gene mutations are absent in NMU-induced mammary carcinomas from aging rats
Carcinogenesis 2000 21: 1917-1922; doi:10.1093/carcin/21.10.1917 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

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