Carcinogenesis

ACCELERATED PAPER:

Masahiro Tsutsumi, Mitsuko Masutani, Tadashige Nozaki, Osamu Kusuoka, Toshifumi Tsujiuchi, Hitoshi Nakagama, Hiroshi Suzuki, Yoichi Konishi, and Takashi Sugimura

Increased susceptibility of poly(ADP-ribose) polymerase-1 knockout mice to nitrosamine carcinogenicity
Carcinogenesis 2001 22: 1-3; doi:10.1093/carcin/22.1.1 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Frederick W. Wiese, Patricia A. Thompson, and Fred F. Kadlubar

Carcinogen substrate specificity of human COX-1 and COX-2
Carcinogenesis 2001 22: 5-10; doi:10.1093/carcin/22.1.5 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Nan Song, Wen Tan, Deyin Xing, and Dongxin Lin

CYP 1A1 polymorphism and risk of lung cancer in relation to tobacco smoking: a case–control study in China
Carcinogenesis 2001 22: 11-16; doi:10.1093/carcin/22.1.11 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

CANCER BIOLOGY:

M. Richter, M. Weiss, I. Weinberger, G. Fürstenberger, and B. Marian

Growth inhibition and induction of apoptosis in colorectal tumor cells by cyclooxygenase inhibitors
Carcinogenesis 2001 22: 17-25; doi:10.1093/carcin/22.1.17 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Asta Försti, Liping Luo, Igor Vorechovsky, Magnus Söderberg, Paul Lichtenstein, and Kari Hemminki

Allelic imbalance on chromosomes 13 and 17 and mutation analysis of BRCA1 and BRCA2 genes in monozygotic twins concordant for breast cancer
Carcinogenesis 2001 22: 27-33; doi:10.1093/carcin/22.1.27 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Dianhua Qiao, Elias D. Stratagouleas, and Jesse D. Martinez

Activation and role of mitogen-activated protein kinases in deoxycholic acid-induced apoptosis
Carcinogenesis 2001 22: 35-41; doi:10.1093/carcin/22.1.35 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

R. Hughes and I.R. Rowland

Stimulation of apoptosis by two prebiotic chicory fructans in the rat colon
Carcinogenesis 2001 22: 43-47; doi:10.1093/carcin/22.1.43 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Eric Le Ferrec, Guennady Ilyin, Karine Mahéo, Caroline Bardiau, Arnaud Courtois, André Guillouzo, and Fabrice Morel

Differential effects of oltipraz on CYP1A and CYP2B in rat lung
Carcinogenesis 2001 22: 49-55; doi:10.1093/carcin/22.1.49 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Andrew F. Olshan, Mark C. Weissler, Mary A. Watson, and Douglas A. Bell

Risk of head and neck cancer and the alcohol dehydrogenase 3 genotype
Carcinogenesis 2001 22: 57-61; doi:10.1093/carcin/22.1.57 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

S.W. Baxter, E.J. Thomas, and I.G. Campbell

GSTM1 null polymorphism and susceptibility to endometriosis and ovarian cancer
Carcinogenesis 2001 22: 63-66; doi:10.1093/carcin/22.1.63 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Amanda B. Spurdle, Penelope M. Webb, David M. Purdie, Xiaoqing Chen, Adele Green, and Georgia Chenevix-Trench

Polymorphisms at the glutathione S-transferase GSTM1, GSTT1 and GSTP1 loci: risk of ovarian cancer by histological subtype
Carcinogenesis 2001 22: 67-72; doi:10.1093/carcin/22.1.67 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Heather E. Kleiner, Suryanarayana V. Vulimiri, Laura Miller, William H. Johnson, Jr, Christian P. Whitman, and John DiGiovanni

Oral administration of naturally occurring coumarins leads to altered phase I and II enzyme activities and reduced DNA adduct formation by polycyclic aromatic hydrocarbons in various tissues of SENCAR mice
Carcinogenesis 2001 22: 73-82; doi:10.1093/carcin/22.1.73 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Susan M. Fischer, Marilyn Lee, and Ronald A. Lubet

Difluoromethylornithine is effective as both a preventive and therapeutic agent against the development of UV carcinogenesis in SKH hairless mice
Carcinogenesis 2001 22: 83-88; doi:10.1093/carcin/22.1.83 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Janis E. Hulla, John E. French, and June K. Dunnick

Chromosome 11 allelotypes reflect a mechanism of chemical carcinogenesis in heterozygous p53-deficient mice
Carcinogenesis 2001 22: 89-98; doi:10.1093/carcin/22.1.89 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

John E. French, Gregory D. Lacks, Carol Trempus, June K. Dunnick, Julie Foley, Joel Mahler, Raymond R. Tice, and Raymond W. Tennant

Loss of heterozygosity frequency at the Trp53 locus in p53-deficient (+/–) mouse tumors is carcinogen-and tissue-dependent
Carcinogenesis 2001 22: 99-106; doi:10.1093/carcin/22.1.99 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Bogdan Prokopczyk, Neil Trushin, Joanna Leszczynska, Steven E. Waggoner, and Karam El-Bayoumy

Human cervical tissue metabolizes the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, via -hydroxylation and carbonyl reduction pathways
Carcinogenesis 2001 22: 107-114; doi:10.1093/carcin/22.1.107 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Alexandra C. Miller, Steve Mog, LuAnn McKinney, Lei Luo, Jennifer Allen, Jiaquan Xu, and Natalie Page

Neoplastic transformation of human osteoblast cells to the tumorigenic phenotype by heavy metal–tungsten alloy particles: induction of genotoxic effects
Carcinogenesis 2001 22: 115-125; doi:10.1093/carcin/22.1.115 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

M.V.W. Wijnands, H.C. Schoterman, J.P. Bruijntjes, V.M.H. Hollanders, and R.A. Woutersen

Effect of dietary galacto-oligosaccharides on azoxymethane-induced aberrant crypt foci and colorectal cancer in Fischer 344 rats
Carcinogenesis 2001 22: 127-132; doi:10.1093/carcin/22.1.127 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Volker M. Arlt, Heinz H. Schmeiser, and Gerd P. Pfeifer

Sequence-specific detection of aristolochic acid–DNA adducts in the human p53 gene by terminal transferase-dependent PCR
Carcinogenesis 2001 22: 133-140; doi:10.1093/carcin/22.1.133 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Chiara Mondello, Maura Faravelli, Loredana Pipitone, Anna Rollier, Aldo Di Leonardo, and Elena Giulotto

Gene amplification in fibroblasts from ataxia telangiectasia (AT) patients and in X-ray hypersensitive AT-like Chinese hamster mutants
Carcinogenesis 2001 22: 141-145; doi:10.1093/carcin/22.1.141 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Jennifer L. Torino, Melissa S. Burger, Catherine A. Reznikoff, and Santhanam Swaminathan

Role of TP53 in repair of N-(deoxyguanosin-8-yl)-4-aminobiphenyl adducts in human transitional cell carcinoma of the urinary bladder
Carcinogenesis 2001 22: 147-154; doi:10.1093/carcin/22.1.147 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Nicola Brookman-Amissah, Alan G. Mackay, and Peter F. Swann

Isolation and sequencing of the cDNA of a novel cytochrome P450 from rat oesophagus
Carcinogenesis 2001 22: 155-160; doi:10.1093/carcin/22.1.155 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brinda Mahadevan, Andreas Luch, Albrecht Seidel, Jill C. Pelling, and William M. Baird

Effects of the (–)-anti-11R,12S-dihydrodiol 13S,14R-epoxide of dibenzo[a,l]pyrene on DNA adduct formation and cell cycle arrest in human diploid fibroblasts
Carcinogenesis 2001 22: 161-169; doi:10.1093/carcin/22.1.161 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Stephen D. Dertinger, Daniel A. Nazarenko, Allen E. Silverstone, and Thomas A. Gasiewicz

Aryl hydrocarbon receptor signaling plays a significant role in mediating benzo[a]pyrene- and cigarette smoke condensate-induced cytogenetic damage in vivo
Carcinogenesis 2001 22: 171-177; doi:10.1093/carcin/22.1.171 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Li-Jun Mi, Wenren Chaung, Robert Horowitz, George W. Teebor, and Robert J. Boorstein

Excessive base excision repair of 5-hydroxymethyluracil from DNA induces apoptosis in Chinese hamster V79 cells containing mutant p53
Carcinogenesis 2001 22: 179-186; doi:10.1093/carcin/22.1.179 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

SHORT COMMUNICATION:

Hideki Kamitani, Seijiro Taniura, Hiroshi Ikawa, Takashi Watanabe, Uddhav P. Kelavkar, and Thomas E. Eling

Expression of 15-lipoxygenase-1 is regulated by histone acetylation in human colorectal carcinoma
Carcinogenesis 2001 22: 187-191; doi:10.1093/carcin/22.1.187 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Takuji Tanaka, Masayo Maeda, Hiroyuki Kohno, Manabu Murakami, Seiko Kagami, Masaki Miyake, and Keiji Wada

Inhibition of azoxymethane-induced colon carcinogenesis in male F344 rats by the citrus limonoids obacunone and limonin
Carcinogenesis 2001 22: 193-198; doi:10.1093/carcin/22.1.193 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

R. Hughes, A.J. Cross, J.R.A. Pollock, and S. Bingham

Dose-dependent effect of dietary meat on endogenous colonic N-nitrosation
Carcinogenesis 2001 22: 199-202; doi:10.1093/carcin/22.1.199 [Abstract] [FREE Full Text] [PDF] Erratum [Request Permissions]  

Marcia d.M.von Pressentin, Michael Chen, and Joseph B. Guttenplan

Mutagenesis induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N-nitrosonornicotine in lacZ upper aerodigestive tissue and liver and inhibition by green tea
Carcinogenesis 2001 22: 203-206; doi:10.1093/carcin/22.1.203 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

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