Carcinogenesis

REVIEW:

Geoffrey A. Wood, James E. Korkola, and Michael C. Archer

Tissue-specific resistance to cancer development in the rat: phenotypes of tumor-modifier genes
Carcinogenesis 2002 23: 1-9; doi:10.1093/carcin/23.1.1 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

CANCER BIOLOGY:

Paola Palozza, Simona Serini, Nicola Maggiano, Mara Angelini, Alma Boninsegna, Fiorella Di Nicuolo, Franco O. Ranelletti, and Gabriella Calviello

Induction of cell cycle arrest and apoptosis in human colon adenocarcinoma cell lines by ß-carotene through down-regulation of cyclin A and Bcl-2 family proteins
Carcinogenesis 2002 23: 11-18; doi:10.1093/carcin/23.1.11 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Koichi Nakakuki, Issei Imoto, Atiphan Pimkhaokham, Yoji Fukuda, Yutaka Shimada, Masayuki Imamura, Teruo Amagasa, and Johji Inazawa

Novel targets for the 18p11.3 amplification frequently observed in esophageal squamous cell carcinomas
Carcinogenesis 2002 23: 19-24; doi:10.1093/carcin/23.1.19 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Yuji Kamiya, Monika Puzianowska-Kuznicka, Peter McPhie, Janusz Nauman, Sheue-yann Cheng, and Alicja Nauman

Expression of mutant thyroid hormone nuclear receptors is associated with human renal clear cell carcinoma
Carcinogenesis 2002 23: 25-33; doi:10.1093/carcin/23.1.25 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Martin Loignon and Elliot A. Drobetsky

The initiation of UV-induced G₁ arrest in human cells is independent of the p53/p21/pRb pathway but can be attenuated through expression of the HPV E7 oncoprotein
Carcinogenesis 2002 23: 35-45; doi:10.1093/carcin/23.1.35 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Tanja Schwerdtle, Albrecht Seidel, and Andrea Hartwig

Effect of soluble and particulate nickel compounds on the formation and repair of stable benzo[a]pyrene DNA adducts in human lung cells
Carcinogenesis 2002 23: 47-53; doi:10.1093/carcin/23.1.47 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

N.J. Hodges and J.K. Chipman

Down-regulation of the DNA-repair endonuclease 8-oxo-guanine DNA glycosylase 1 (hOGG1) by sodium dichromate in cultured human A549 lung carcinoma cells
Carcinogenesis 2002 23: 55-60; doi:10.1093/carcin/23.1.55 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Sahar Sibani, Stepan Melnyk, Igor P. Pogribny, Wei Wang, Francois Hiou-Tim, Liyuan Deng, Jacquetta Trasler, S.Jill James, and Rima Rozen

Studies of methionine cycle intermediates (SAM, SAH), DNA methylation and the impact of folate deficiency on tumor numbers in Min mice
Carcinogenesis 2002 23: 61-65; doi:10.1093/carcin/23.1.61 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Makoto Futaki, Takehito Igarashi, Shinji Watanabe, Sachiko Kajigaya, Atsushi Tatsuguchi, Jianxiang Wang, and Johnson M. Liu

The FANCG Fanconi anemia protein interacts with CYP2E1: possible role in protection against oxidative DNA damage
Carcinogenesis 2002 23: 67-72; doi:10.1093/carcin/23.1.67 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Victor de Lédinghen, Hailing Liu, Fan Zhang, Chau R. Lo, Kotha Subbaramaiah, Andrew J. Dannenberg, and Mark J. Czaja

Induction of cyclooxygenase-2 by tumor promoters in transformed and cytochrome P450 2E1-expressing hepatocytes
Carcinogenesis 2002 23: 73-79; doi:10.1093/carcin/23.1.73 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Rongxian Jin, Vincent T.-K. Chow, Puay-Hoon Tan, S.Thameem Dheen, Wei Duan, and Boon-Huat Bay

Metallothionein 2A expression is associated with cell proliferation in breast cancer
Carcinogenesis 2002 23: 81-86; doi:10.1093/carcin/23.1.81 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Matthias P.A. Ebert, Guo Fei, Sabine Kahmann, Oliver Müller, Jun Yu, Joseph J.Y. Sung, and Peter Malfertheiner

Increased ß-catenin mRNA levels and mutational alterations of the APC and ß-catenin gene are present in intestinal-type gastric cancer
Carcinogenesis 2002 23: 87-91; doi:10.1093/carcin/23.1.87 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ming H. Wu, Jei H. Chang, and Benjamin Y.M. Yung

Resistance to UV-induced cell-killing in nucleophosmin/B23 over-expressed NIH 3T3 fibroblasts: enhancement of DNA repair and up-regulation of PCNA in association with nucleophosmin/B23 over-expression
Carcinogenesis 2002 23: 93-100; doi:10.1093/carcin/23.1.93 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

MOLECULAR EPIDEMIOLOGY AND CANCER PREVENTION:

Juan Alguacil, Miquel Porta, Núria Malats, Timo Kauppinen, Manolis Kogevinas, Fernando G. Benavides, Timo Partanen, and Alfredo Carrato

Occupational exposure to organic solvents and K-ras mutations in exocrine pancreatic cancer
Carcinogenesis 2002 23: 101-106; doi:10.1093/carcin/23.1.101 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Gillian Hawcroft, Mark D'Amico, Chris Albanese, Alexander F. Markham, Richard G. Pestell, and Mark A. Hull

Indomethacin induces differential expression of ß-catenin, -catenin and T-cell factor target genes in human colorectal cancer cells
Carcinogenesis 2002 23: 107-114; doi:10.1093/carcin/23.1.107 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

CARCINOGENESIS:

Sophie Langouët, Axel Paehler, Dieter H. Welti, Nathalie Kerriguy, André Guillouzo, and Robert J. Turesky

Differential metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in rat and human hepatocytes
Carcinogenesis 2002 23: 115-122; doi:10.1093/carcin/23.1.115 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Xiaoxin Chen, Yu Ding, Chang-Gong Liu, Samer Mikhail, and Chung S. Yang

Overexpression of glucose-regulated protein 94 (Grp94) in esophageal adenocarcinomas of a rat surgical model and humans
Carcinogenesis 2002 23: 123-130; doi:10.1093/carcin/23.1.123 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Wenge Shi and Michael N. Gould

Induction of cytostasis in mammary carcinoma cells treated with the anticancer agent perillyl alcohol
Carcinogenesis 2002 23: 131-142; doi:10.1093/carcin/23.1.131 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ruby John Anto, Asok Mukhopadhyay, Kate Denning, and Bharat B. Aggarwal

Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: its suppression by ectopic expression of Bcl-2 and Bcl-xl
Carcinogenesis 2002 23: 143-150; doi:10.1093/carcin/23.1.143 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Wei Qu, Carl D. Bortner, Teruaki Sakurai, Michael J. Hobson, and Michael P. Waalkes

Acquisition of apoptotic resistance in arsenic-induced malignant transformation: role of the JNK signal transduction pathway
Carcinogenesis 2002 23: 151-159; doi:10.1093/carcin/23.1.151 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Djuana M.E Harvell, Tracy E. Strecker, Benjamin Xie, Karen L. Pennington, Rodney D. McComb, and James D. Shull

Dietary energy restriction inhibits estrogen-induced mammary, but not pituitary, tumorigenesis in the ACI rat
Carcinogenesis 2002 23: 161-169; doi:10.1093/carcin/23.1.161 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Zheng Wu, Pramod Upadhyaya, Steven G. Carmella, Stephen S. Hecht, and Cheryl L. Zimmerman

Disposition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in bile duct-cannulated rats: Stereoselective metabolism and tissue distribution
Carcinogenesis 2002 23: 171-179; doi:10.1093/carcin/23.1.171 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Carola Berking, Richelle Takemoto, Robert L. Binder, Scott M. Hartman, Dirk J. Ruiter, Patricia M. Gallagher, Stuart R. Lessin, and Meenhard Herlyn

Photocarcinogenesis in human adult skin grafts
Carcinogenesis 2002 23: 181-187; doi:10.1093/carcin/23.1.181 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ying Yan, Zhao-Zhu Zeng, Shin Higashi, Ayumi Denda, Yoichi Konishi, Shunzo Onishi, Hikaru Ueno, Ken Higashi, and Hiroshi Hiai

Resistance of DRH strain rats to chemical carcinogenesis of liver: genetic analysis of later progression stage
Carcinogenesis 2002 23: 189-196; doi:10.1093/carcin/23.1.189 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

SHORT COMMUNICATIONS:

Tsuneyuki Ubagai, Masako Ochiai, Toshihiko Kawamori, Hiroshi Imai, Takashi Sugimura, Minako Nagao, and Hitoshi Nakagama

Efficient induction of rat large intestinal tumors with a new spectrum of mutations by intermittent administration of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in combination with a high fat diet
Carcinogenesis 2002 23: 197-200; doi:10.1093/carcin/23.1.197 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Hemant K. Roy, Bola F. Olusola, Dahn L. Clemens, William J. Karolski, Anne Ratashak, Henry T. Lynch, and Thomas C. Smyrk

AKT proto-oncogene overexpression is an early event during sporadic colon carcinogenesis
Carcinogenesis 2002 23: 201-205; doi:10.1093/carcin/23.1.201 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Yujing Zhang, Shu-Yuan Chen, Taming Hsu, and Regina M. Santella

Immunohistochemical detection of malondialdehyde–DNA adducts in human oral mucosa cells
Carcinogenesis 2002 23: 207-211; doi:10.1093/carcin/23.1.207 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Michel Lebel

Increased frequency of DNA deletions in pink-eyed unstable mice carrying a mutation in the Werner syndrome gene homologue
Carcinogenesis 2002 23: 213-216; doi:10.1093/carcin/23.1.213 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Russell D. Klein and Susan M. Fischer

Black tea polyphenols inhibit IGF-I-induced signaling through Akt in normal prostate epithelial cells and Du145 prostate carcinoma cells
Carcinogenesis 2002 23: 217-221; doi:10.1093/carcin/23.1.217 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

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