Carcinogenesis

COMMENTARY:

Tapas K. Hazra, Tadahide Izumi, Y.Wah Kow, and Sankar Mitra

The discovery of a new family of mammalian enzymes for repair of oxidatively damaged DNA, and its physiological implications
Carcinogenesis 2003 24: 155-157; doi:10.1093/carcin/24.2.155 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Anna-Marija Helt and Denise A. Galloway

Mechanisms by which DNA tumor virus oncoproteins target the Rb family of pocket proteins
Carcinogenesis 2003 24: 159-169; doi:10.1093/carcin/24.2.159 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

CANCER BIOLOGY:

Judith Brown, Jim O’Prey, and P.R. Harrison

Enhanced sensitivity of human oral tumours to the flavonol, morin, during cancer progression: involvement of the Akt and stress kinase pathways
Carcinogenesis 2003 24: 171-177; doi:10.1093/carcin/24.2.171 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Z.Dave Sharp, Wen-Hwa Lee, Alexander Yu Nikitin, Andrea Flesken-Nikitin, Yuji Ikeno, Robert Reddick, Arlan G. Richardson, and James F. Nelson

Minimal effects of dietary restriction on neuroendocrine carcinogenesis in Rb^+/– mice
Carcinogenesis 2003 24: 179-183; doi:10.1093/carcin/24.2.179 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

H. Zhang, K. Satyamoorthy, M. Herlyn, and I. Rosdahl

All-trans retinoic acid (atRA) differentially induces apoptosis in matched primary and metastatic melanoma cells – a speculation on damage effect of atRA via mitochondrial dysfunction and cell cycle redistribution
Carcinogenesis 2003 24: 185-191; doi:10.1093/carcin/24.2.185 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Michael G. House, MingZhou Guo, Christine Iacobuzio-Donahue, and James G. Herman

Molecular progression of promoter methylation in intraductal papillary mucinous neoplasms (IPMN) of the pancreas
Carcinogenesis 2003 24: 193-198; doi:10.1093/carcin/24.2.193 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Linda S. Gutierrez, Mark Suckow, Jack Lawler, Victoria A. Ploplis, and Francis J. Castellino

Thrombospondin 1—a regulator of adenoma growth and carcinoma progression in the APC^Min/+ mouse model
Carcinogenesis 2003 24: 199-207; doi:10.1093/carcin/24.2.199 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Addanki P. Kumar, Gretchen E. Garcia, Jon Orsborn, Victor A. Levin, and Thomas J. Slaga

2-Methoxyestradiol interferes with NFB transcriptional activity in primitive neuroectodermal brain tumors: implications for management
Carcinogenesis 2003 24: 209-216; doi:10.1093/carcin/24.2.209 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Kyoung-Jin Sohn, Monica Choi, Jacquelin Song, Sofeene Chan, Alan Medline, Steven Gallinger, and Young-In Kim

Msh2 deficiency enhances somatic Apc and p53 mutations in Apc+/–Msh2–/– mice
Carcinogenesis 2003 24: 217-224; doi:10.1093/carcin/24.2.217 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Aijin Wang, Jing Gu, Kimberly Judson-Kremer, K.Leslie Powell, Harsha Mistry, Padmaja Simhambhatla, C. Marcelo Aldaz, Sally Gaddis, and Michael C. MacLeod

Response of human mammary epithelial cells to DNA damage induced by BPDE: involvement of novel regulatory pathways
Carcinogenesis 2003 24: 225-234; doi:10.1093/carcin/24.2.225 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ha Won Kim, Akira Murakami, Marshall V. Williams, and Hajime Ohigashi

Mutagenicity of reactive oxygen and nitrogen species as detected by co-culture of activated inflammatory leukocytes and AS52 cells
Carcinogenesis 2003 24: 235-241; doi:10.1093/carcin/24.2.235 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Jing Wu, Harry Hua Xiang Xia, Shui Ping Tu, Dai Ming Fan, Marie Chia Mi Lin, Hsiang Fu Kung, Shiu Kum Lam, and Benjamin Chun Yu Wong

15-Lipoxygenase-1 mediates cyclooxygenase-2 inhibitor-induced apoptosis in gastric cancer
Carcinogenesis 2003 24: 243-247; doi:10.1093/carcin/24.2.243 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

John M. Hinz, Thomas Helleday, and Mark Meuth

Reduced apoptotic response to camptothecin in CHO cells deficient in XRCC3
Carcinogenesis 2003 24: 249-253; doi:10.1093/carcin/24.2.249 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

MOLECULAR EPIDEMIOLOGY AND CANCER PREVENTION:

Fekadu Kassie, Maria Uhl, Sylvie Rabot, Bettina Grasl-Kraupp, Ruud Verkerk, Michael Kundi, Monika Chabicovsky, Rolf Schulte-Hermann, and Siegfried Knasmüller

Chemoprevention of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ)-induced colonic and hepatic preneoplastic lesions in the F344 rat by cruciferous vegetables administered simultaneously with the carcinogen
Carcinogenesis 2003 24: 255-261; doi:10.1093/carcin/24.2.255 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Gayle A. Orner, W.-Mohaiza Dashwood, Carmen A. Blum, G. Darío Díaz, Qingjie Li, and Roderick H. Dashwood

Suppression of tumorigenesis in the Apc^min mouse: down-regulation of ß-catenin signaling by a combination of tea plus sulindac
Carcinogenesis 2003 24: 263-267; doi:10.1093/carcin/24.2.263 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Yun-Ling Zheng, Christopher A. Loffredo, Zhipeng Yu, Raymond T. Jones, Mark J. Krasna, Anthony J. Alberg, Rex Yung, Donna Perlmutter, Lindsey Enewold, Curtis C. Harris, and Peter G. Shields

Bleomycin-induced chromosome breaks as a risk marker for lung cancer: a case-control study with population and hospital controls
Carcinogenesis 2003 24: 269-274; doi:10.1093/carcin/24.2.269 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

J.H. Barrett, G. Smith, R. Waxman, N. Gooderham, T. Lightfoot, R.C. Garner, K. Augustsson, C.R. Wolf, D.T. Bishop, D. Forman, and The Colorectal Cancer Study Group

Investigation of interaction between N-acetyltransferase 2 and heterocyclic amines as potential risk factors for colorectal cancer
Carcinogenesis 2003 24: 275-282; doi:10.1093/carcin/24.2.275 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brenda Diergaarde, Winny L. van Geloof, Goos N.P. van Muijen, Frans J. Kok, and Ellen Kampman

Dietary factors and the occurrence of truncating APC mutations in sporadic colon carcinomas: a Dutch population-based study
Carcinogenesis 2003 24: 283-290; doi:10.1093/carcin/24.2.283 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Hansen L. Wong, Sharon E. Murphy, Mingyao Wang, and Stephen S. Hecht

Comparative metabolism of N-nitrosopiperidine and N-nitrosopyrrolidine by rat liver and esophageal microsomes and cytochrome P450 2A3
Carcinogenesis 2003 24: 291-300; doi:10.1093/carcin/24.2.291 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

CARCINOGENESIS:

Werner Kempf, Marshall E. Kadin, Ann M. Dvorak, Carol C. Lord, Günter Burg, Norman L. Letvin, and Igor J. Koralnik

Endogenous retroviral elements, but not exogenous retroviruses, are detected in CD30-positive lymphoproliferative disorders of the skin
Carcinogenesis 2003 24: 301-306; doi:10.1093/carcin/24.2.301 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Mei Dong, Kishore Guda, Prashant R. Nambiar, Anahita Rezaie, Glenn S. Belinsky, Gérard Lambeau, Charles Giardina, and Daniel W. Rosenberg

Inverse association between phospholipase A₂ and COX-2 expression during mouse colon tumorigenesis
Carcinogenesis 2003 24: 307-315; doi:10.1093/carcin/24.2.307 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Feng Chu, Nancy E. Ward, and Catherine A. O’Brian

PKC isozyme S-cysteinylation by cystine stimulates the pro-apoptotic isozyme PKC and inactivates the oncogenic isozyme PKC
Carcinogenesis 2003 24: 317-325; doi:10.1093/carcin/24.2.317 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Jeroen Buters, Leticia Quintanilla-Martinez, Wolfgang Schober, Volker J. Soballa, Josef Hintermair, Thomas Wolff, Frank J. Gonzalez, and Helmut Greim

CYP1B1 determines susceptibility to low doses of 7,12-dimethylbenz[a]anthracene-induced ovarian cancers in mice: correlation of CYP1B1-mediated DNA adducts with carcinogenicity
Carcinogenesis 2003 24: 327-334; doi:10.1093/carcin/24.2.327 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Elsayed I. Salim, Hideki Wanibuchi, Keiichirou Morimura, Min Wei, Makoto Mitsuhashi, Kaoru Yoshida, Ginji Endo, and Shoji Fukushima

Carcinogenicity of dimethylarsinic acid in p53 heterozygous knockout and wild-type C57BL/6J mice
Carcinogenesis 2003 24: 335-342; doi:10.1093/carcin/24.2.335 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Cynthia S.M. Wong and Peter R. Gibson

The trophic effect of dietary fibre is not associated with a change in total crypt number in the distal colon of rats
Carcinogenesis 2003 24: 343-348; doi:10.1093/carcin/24.2.343 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

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