Carcinogenesis

REVIEW:

Patricia L. Opresko, Wen-Hsing Cheng, Cayetano von Kobbe, Jeanine A. Harrigan, and Vilhelm A. Bohr

Werner syndrome and the function of the Werner protein; what they can teach us about the molecular aging process.
Carcinogenesis Advance Access published on March 28, 2003
Carcinogenesis 2003 24: 791-802; doi:10.1093/carcin/bgg034 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

COMMENTARY:

Harry Rubin

Complementary approaches to understanding the role of proteases and their natural inhibitors in neoplastic development: retrospect and prospect
Carcinogenesis Advance Access published on March 28, 2003
Carcinogenesis 2003 24: 803-816; doi:10.1093/carcin/bgg020 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Peter Klatt and Manuel Serrano

Engineering cancer resistance in mice
Carcinogenesis Advance Access published on April 11, 2003
Carcinogenesis 2003 24: 817-826; doi:10.1093/carcin/bgg057 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

CANCER BIOLOGY:

Jun Li, Ping Jiang, Megan Robinson, Theodore S. Lawrence, and Yi Sun

AMPK-ß1 subunit is a p53-independent stress responsive protein that inhibits tumor cell growth upon forced expression
Carcinogenesis Advance Access published on March 28, 2003
Carcinogenesis 2003 24: 827-834; doi:10.1093/carcin/bgg032 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Elisabeth Schausberger, Robert Eferl, Wolfram Parzefall, Monica Chabikovsky, Paul Breit, Erwin F. Wagner, Rolf Schulte-Hermann, and Bettina Grasl-Kraupp

Induction of DNA synthesis in primary mouse hepatocytes is associated with nuclear pro-transforming growth factor and erbb-1 and is independent of c-jun
Carcinogenesis Advance Access published on March 28, 2003
Carcinogenesis 2003 24: 835-841; doi:10.1093/carcin/bgg027 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Maureen E. Fitch, Irina V. Cross, and James M. Ford

p53 responsive nucleotide excision repair gene products p48 and XPC, but not p53, localize to sites of UV-irradiation-induced DNA damage, in vivo
Carcinogenesis Advance Access published on March 28, 2003
Carcinogenesis 2003 24: 843-850; doi:10.1093/carcin/bgg031 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Raffaella Villa, Marco Folini, Chiara Della Porta, Alessandra Valentini, Marzia Pennati, Maria Grazia Daidone, and Nadia Zaffaroni

Inhibition of telomerase activity by geldanamycin and 17-allylamino, 17-demethoxygeldanamycin in human melanoma cells
Carcinogenesis Advance Access published on March 28, 2003
Carcinogenesis 2003 24: 851-859; doi:10.1093/carcin/bgg028 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Masanobu Abe, Satoshi Yamashita, Takashi Kuramoto, Yoshikazu Hirayama, Tetsuya Tsukamoto, Tsutomu Ohta, Masae Tatematsu, Misao Ohki, Tsuyoshi Takato, Takashi Sugimura, and Toshikazu Ushijima

Global expression analysis of N-methyl-N'-nitro-N-nitrosoguanidine-induced rat stomach carcinomas using oligonucleotide microarrays
Carcinogenesis Advance Access published on March 28, 2003
Carcinogenesis 2003 24: 861-867; doi:10.1093/carcin/bgg030 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

MOLECULAR EPIDEMIOLOGY AND CANCER PREVENTION:

Abdalla M. El-Mowafy and Moussa Alkhalaf

Resveratrol activates adenylyl-cyclase in human breast cancer cells: a novel, estrogen receptor-independent cytostatic mechanism
Carcinogenesis 2003 24: 869-873; doi:10.1093/carcin/bgg015 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Rayjean J. Hung, Paolo Boffetta, Jürgen Brockmöller, Dorota Butkiewicz, Ingolf Cascorbi, Margie L. Clapper, Seymour Garte, Aage Haugen, Ari Hirvonen, Sisko Anttila, Ivan Kalina, Loïc Le Marchand, Stephanie J. London, Agneta Rannug, Marjorie Romkes, Jan Salagovic, Bernadette Schoket, Laura Gaspari, and Emanuela Taioli

CYP1A1 and GSTM1 genetic polymorphisms and lung cancer risk in Caucasian non-smokers: a pooled analysis
Carcinogenesis Advance Access published on March 28, 2003
Carcinogenesis 2003 24: 875-882; doi:10.1093/carcin/bgg026 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Tasha R. Smith, Mark S. Miller, Kurt K. Lohman, L.Douglas Case, and Jennifer J. Hu

DNA damage and breast cancer risk
Carcinogenesis Advance Access published on March 28, 2003
Carcinogenesis 2003 24: 883-889; doi:10.1093/carcin/bgg037 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Dong Xiao, Sanjay K. Srivastava, Karen L. Lew, Yan Zeng, Pamela Hershberger, Candace S. Johnson, Donald L. Trump, and Shivendra V. Singh

Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits proliferation of human prostate cancer cells by causing G₂/M arrest and inducing apoptosis
Carcinogenesis Advance Access published on March 28, 2003
Carcinogenesis 2003 24: 891-897; doi:10.1093/carcin/bgg023 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Bjørn A. Nexø, Ulla Vogel, Anja Olsen, Tina Ketelsen, Zuzanna Bukowy, Birthe L. Thomsen, Håkan Wallin, Kim Overvad, and Anne Tjønneland

A specific haplotype of single nucleotide polymorphisms on chromosome 19q13.2–3 encompassing the gene RAI is indicative of post-menopausal breast cancer before age 55
Carcinogenesis Advance Access published on March 28, 2003
Carcinogenesis 2003 24: 899-904; doi:10.1093/carcin/bgg043 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Jianhui Zhang, Wolfgang A. Schulz, Yan Li, Rui Wang, Rainer Zotz, Denggui Wen, David Siegel, David Ross, Helmut E. Gabbert, and Mario Sarbia

Association of NAD(P)H: quinone oxidoreductase 1 (NQO1) C609T polymorphism with esophageal squamous cell carcinoma in a German Caucasian and a northern Chinese population
Carcinogenesis Advance Access published on March 28, 2003
Carcinogenesis 2003 24: 905-909; doi:10.1093/carcin/bgg019 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Manabu Yasui, Saburo Matsui, Y.R.Santosh Laxmi, Naomi Suzuki, Sung Yeon Kim, Shinya Shibutani, and Tomonari Matsuda

Mutagenic events induced by 4-hydroxyequilin in supF shuttle vector plasmid propagated in human cells
Carcinogenesis Advance Access published on March 28, 2003
Carcinogenesis 2003 24: 911-917; doi:10.1093/carcin/bgg029 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Lesley E. Rhodes, Hassan Shahbakhti, Richard M. Azurdia, Ralf M.W. Moison, Marie-Jose S.T. Steenwinkel, Marie I. Homburg, Michael P. Dean, F. McArdle, Gerard M.J. Beijersbergen van Henegouwen, Bernd Epe, and Arie A. Vink

Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers
Carcinogenesis Advance Access published on March 28, 2003
Carcinogenesis 2003 24: 919-925; doi:10.1093/carcin/bgg038 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Praveen K. Vayalil, Craig A. Elmets, and Santosh K. Katiyar

Treatment of green tea polyphenols in hydrophilic cream prevents UVB-induced oxidation of lipids and proteins, depletion of antioxidant enzymes and phosphorylation of MAPK proteins in SKH-1 hairless mouse skin
Carcinogenesis Advance Access published on March 28, 2003
Carcinogenesis 2003 24: 927-936; doi:10.1093/carcin/bgg025 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Joanne Kotsopoulos, Kyoung-Jin Sohn, Rochelle Martin, Monica Choi, Richard Renlund, Colin Mckerlie, Stephen W. Hwang, Alan Medline, and Young-In J. Kim

Dietary folate deficiency suppresses N-methyl-N-nitrosourea-induced mammary tumorigenesis in rats
Carcinogenesis Advance Access published on March 28, 2003
Carcinogenesis 2003 24: 937-944; doi:10.1093/carcin/bgg036 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Susan M. Fischer, Claudio J. Conti, Jaye Viner, C.Marcelo Aldaz, and Ronald A. Lubet

Celecoxib and difluoromethylornithine in combination have strong therapeutic activity against UV-induced skin tumors in mice
Carcinogenesis Advance Access published on March 28, 2003
Carcinogenesis 2003 24: 945-952; doi:10.1093/carcin/bgg046 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

CARCINOGENESIS:

Takeki Tsutsui, Shin-ichi Kumakura, Yukiko Tamura, Takeo W. Tsutsui, Mizuki Sekiguchi, Tokihiro Higuchi, and J.Carl Barrett

Immortal, telomerase-negative cell lines derived from a Li-Fraumeni syndrome patient exhibit telomere length variability and chromosomal and minisatellite instabilities
Carcinogenesis Advance Access published on March 28, 2003
Carcinogenesis 2003 24: 953-965; doi:10.1093/carcin/bgg024 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Tanja Schwerdtle, Ingo Walter, Iris Mackiw, and Andrea Hartwig

Induction of oxidative DNA damage by arsenite and its trivalent and pentavalent methylated metabolites in cultured human cells and isolated DNA
Carcinogenesis 2003 24: 967-974; doi:10.1093/carcin/bgg018 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Kirstin Meyer, Ju-Seog Lee, Patricia A. Dyck, Wen-Qing Cao, M.Sambasiva Rao, Snorri S. Thorgeirsson, and Janardan K. Reddy

Molecular profiling of hepatocellular carcinomas developing spontaneously in acyl-CoA oxidase deficient mice: comparison with liver tumors induced in wild-type mice by a peroxisome proliferator and a genotoxic carcinogen
Carcinogenesis Advance Access published on March 28, 2003
Carcinogenesis 2003 24: 975-984; doi:10.1093/carcin/bgg040 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Toshihiko Kawamori, Naoaki Uchiya, Takashi Sugimura, and Keiji Wakabayashi

Enhancement of colon carcinogenesis by prostaglandin E₂ administration
Carcinogenesis Advance Access published on March 28, 2003
Carcinogenesis 2003 24: 985-990; doi:10.1093/carcin/bgg033 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

H. Jernström, T.L. Klug, D.W. Sepkovic, H.L. Bradlow, and S.A. Narod

Predictors of the plasma ratio of 2-hydroxyestrone to 16-hydroxyestrone among pre-menopausal, nulliparous women from four ethnic groups
Carcinogenesis Advance Access published on March 28, 2003
Carcinogenesis 2003 24: 991-1005; doi:10.1093/carcin/bgg047 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

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