Carcinogenesis

CANCER BIOLOGY:

T.T.T. Nguyen, E. Tran, T.H. Nguyen, P.T. Do, T.H. Huynh, and H. Huynh

The role of activated MEK-ERK pathway in quercetin-induced growth inhibition and apoptosis in A549 lung cancer cells
Carcinogenesis Advance Access published on December 19, 2003
Carcinogenesis 2004 25: 647-659; doi:10.1093/carcin/bgh052 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Janet C. Lindsey, Meryl E. Lusher, Jennifer A. Anderton, Simon Bailey, Richard J. Gilbertson, Andrew D.J. Pearson, David W. Ellison, and Steven C. Clifford

Identification of tumour-specific epigenetic events in medulloblastoma development by hypermethylation profiling
Carcinogenesis Advance Access published on December 19, 2003
Carcinogenesis 2004 25: 661-668; doi:10.1093/carcin/bgh055 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Timothy J. King and Paul D. Lampe

Mice deficient for the gap junction protein Connexin32 exhibit increased radiation-induced tumorigenesis associated with elevated mitogen-activated protein kinase (p44/Erk1, p42/Erk2) activation
Carcinogenesis Advance Access published on January 23, 2004
Carcinogenesis 2004 25: 669-680; doi:10.1093/carcin/bgh071 [Abstract] [FREE Full Text] [PDF] Supplementary data [Request Permissions]  

Harris Bernstein, Claire M. Payne, Kathleen Kunke, Cara L. Crowley-Weber, Caroline N. Waltmire, Katerina Dvorakova, Hana Holubec, Carol Bernstein, Richard R. Vaillancourt, Deborah A. Raynes, Vincent Guerriero, and Harinder Garewal

A proteomic study of resistance to deoxycholate-induced apoptosis
Carcinogenesis Advance Access published on January 16, 2004
Carcinogenesis 2004 25: 681-692; doi:10.1093/carcin/bgh072 [Abstract] [FREE Full Text] [PDF] Supplementary data [Request Permissions]  

G. Strathdee, B.R. Davies, J.K. Vass, N. Siddiqui, and R. Brown

Cell type-specific methylation of an intronic CpG island controls expression of the MCJ gene
Carcinogenesis Advance Access published on January 16, 2004
Carcinogenesis 2004 25: 693-701; doi:10.1093/carcin/bgh066 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Uwe Wenzel, Alexander Nickel, Sabine Kuntz, and Hannelore Daniel

Ascorbic acid suppresses drug-induced apoptosis in human colon cancer cells by scavenging mitochondrial superoxide anions
Carcinogenesis Advance Access published on January 30, 2004
Carcinogenesis 2004 25: 703-712; doi:10.1093/carcin/bgh079 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

MOLECULAR EPIDEMIOLOGY AND CANCER PREVENTION:

Kyung-Soo Chun, Su-Hyeong Kim, Yong-Sang Song, and Young-Joon Surh

Celecoxib inhibits phorbol ester-induced expression of COX-2 and activation of AP-1 and p38 MAP kinase in mouse skin
Carcinogenesis Advance Access published on January 16, 2004
Carcinogenesis 2004 25: 713-722; doi:10.1093/carcin/bgh076 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Hitomi Kumagai, Ken-ichi Mukaisho, Hiroyuki Sugihara, Koichi Miwa, Gaku Yamamoto, and Takanori Hattori

Thioproline inhibits development of esophageal adenocarcinoma induced by gastroduodenal reflux in rats
Carcinogenesis Advance Access published on January 30, 2004
Carcinogenesis 2004 25: 723-727; doi:10.1093/carcin/bgh067 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Somali Sanyal, Fabiola Festa, Shigeru Sakano, Zhengzhong Zhang, Gunnar Steineck, Ulf Norming, Hans Wijkström, Per Larsson, Rajiv Kumar, and Kari Hemminki

Polymorphisms in DNA repair and metabolic genes in bladder cancer
Carcinogenesis Advance Access published on December 19, 2003
Carcinogenesis 2004 25: 729-734; doi:10.1093/carcin/bgh058 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

M.M. Gaudet, A.F. Olshan, C. Poole, M.C. Weissler, M. Watson, and D.A. Bell

Diet, GSTM1 and GSTT1 and head and neck cancer
Carcinogenesis Advance Access published on December 19, 2003
Carcinogenesis 2004 25: 735-740; doi:10.1093/carcin/bgh054 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Anna Cabanes, Mingyue Wang, Susan Olivo, Sonia DeAssis, Jan-Åke Gustafsson, Galam Khan, and Leena Hilakivi-Clarke

Prepubertal estradiol and genistein exposures up-regulate BRCA1 mRNA and reduce mammary tumorigenesis
Carcinogenesis Advance Access published on January 16, 2004
Carcinogenesis 2004 25: 741-748; doi:10.1093/carcin/bgh065 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Emanuela Barletta, Giuseppe Gorini, Paolo Vineis, Lucia Miligi, Laura Davico, Gabriele Mugnai, Stefania Ciolli, Franco Leoni, Marilena Bertini, Giuseppe Matullo, and Adele Seniori Costantini

Ras gene mutations in patients with acute myeloid leukaemia and exposure to chemical agents
Carcinogenesis Advance Access published on December 19, 2003
Carcinogenesis 2004 25: 749-755; doi:10.1093/carcin/bgh057 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Pavel Vodicka, Rajiv Kumar, Rudolf Stetina, Somali Sanyal, Pavel Soucek, Vincent Haufroid, Maria Dusinska, Miroslava Kuricova, Maria Zamecnikova, Ludovit Musak, Jana Buchancova, Hannu Norppa, Ari Hirvonen, Ludmila Vodickova, Alessio Naccarati, Zora Matousu, and Kari Hemminki

Genetic polymorphisms in DNA repair genes and possible links with DNA repair rates, chromosomal aberrations and single-strand breaks in DNA
Carcinogenesis Advance Access published on January 16, 2004
Carcinogenesis 2004 25: 757-763; doi:10.1093/carcin/bgh064 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Juliet M. Pullar, Susan J. Thomson, Monica J. King, Christopher I. Turnbull, Robyn G. Midwinter, and Mark B. Hampton

The chemopreventive agent phenethyl isothiocyanate sensitizes cells to Fas-mediated apoptosis
Carcinogenesis Advance Access published on January 16, 2004
Carcinogenesis 2004 25: 765-772; doi:10.1093/carcin/bgh063 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Gang Liang, Xiaoping Miao, Yifeng Zhou, Wen Tan, and Dongxin Lin

A functional polymorphism in the SULT1A1 gene (G638A) is associated with risk of lung cancer in relation to tobacco smoking
Carcinogenesis Advance Access published on December 19, 2003
Carcinogenesis 2004 25: 773-778; doi:10.1093/carcin/bgh053 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

CARCINOGENESIS:

Hansruedi Glatt and Walter Meinl

Use of genetically manipulated Salmonella typhimurium strains to evaluate the role of sulfotransferases and acetyltransferases in nitrofen mutagenicity
Carcinogenesis Advance Access published on January 30, 2004
Carcinogenesis 2004 25: 779-786; doi:10.1093/carcin/bgh070 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ronald D. Thomas, Mario R. Green, Chantell Wilson, and Sakeenah Sadrud-Din

Diallyl sulfide inhibits the oxidation and reduction reactions of stilbene estrogens catalyzed by microsomes, mitochondria and nuclei isolated from breast tissue of female ACI rats
Carcinogenesis Advance Access published on August 29, 2003
Carcinogenesis 2004 25: 787-791; doi:10.1093/carcin/bgg161 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Taghreed Almahmeed, Jay O. Boyle, Erik G. Cohen, John F. Carew, Baoheng Du, Nasser K. Altorki, Levy Kopelovich, Jia-Long Fang, Philip Lazarus, Kotha Subbaramaiah, and Andrew J. Dannenberg

Benzo[a]pyrene phenols are more potent inducers of CYP1A1, CYP1B1 and COX-2 than benzo[a]pyrene glucuronides in cell lines derived from the human aerodigestive tract
Carcinogenesis Advance Access published on January 16, 2004
Carcinogenesis 2004 25: 793-799; doi:10.1093/carcin/bgh078 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Hansruedi Glatt, Ulrike Pabel, Walter Meinl, Hanne Frederiksen, Henrik Frandsen, and Eva Muckel

Bioactivation of the heterocyclic aromatic amine 2-amino-3-methyl-9H-pyrido [2,3-b]indole (MeAC) in recombinant test systems expressing human xenobiotic-metabolizing enzymes
Carcinogenesis Advance Access published on January 16, 2004
Carcinogenesis 2004 25: 801-807; doi:10.1093/carcin/bgh077 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Anita Solhaug, Magne Refsnes, Marit Låg, Per E. Schwarze, Trine Husøy, and Jørn A. Holme

Polycyclic aromatic hydrocarbons induce both apoptotic and anti-apoptotic signals in Hepa1c1c7 cells
Carcinogenesis Advance Access published on January 16, 2004
Carcinogenesis 2004 25: 809-819; doi:10.1093/carcin/bgh069 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Yoshinobu Hirose, Kazuya Hata, Toshiya Kuno, Koujiro Yoshida, Keiko Sakata, Yasuhiro Yamada, Takuji Tanaka, Bandaru S. Reddy, and Hideki Mori

Enhancement of development of azoxymethane-induced colonic premalignant lesions in C57BL/KsJ-db/db mice
Carcinogenesis Advance Access published on January 16, 2004
Carcinogenesis 2004 25: 821-825; doi:10.1093/carcin/bgh059 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

A.J. Alija, N. Bresgen, O. Sommerburg, W. Siems, and P.M. Eckl

Cytotoxic and genotoxic effects of ß-carotene breakdown products on primary rat hepatocytes
Carcinogenesis Advance Access published on December 19, 2003
Carcinogenesis 2004 25: 827-831; doi:10.1093/carcin/bgh056 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Marie Stiborová, Markéta Miksanová, Stanislav Smrcek, Christian A. Bieler, Andrea Breuer, Karl A. Klokow, Heinz H. Schmeiser, and Eva Frei

Identification of a genotoxic mechanism for 2-nitroanisole carcinogenicity and of its carcinogenic potential for humans
Carcinogenesis Advance Access published on January 16, 2004
Carcinogenesis 2004 25: 833-840; doi:10.1093/carcin/bgh061 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Reiping Tang, Chung Rong Changchien, Meng-Chih Wu, Chung-Wei Fan, Kwang-Wen Liu, Jinn-Shiun Chen, Huei-Tzu Chien, and Ling-Ling Hsieh

Colorectal cancer without high microsatellite instability and chromosomal instability—an alternative genetic pathway to human colorectal cancer
Carcinogenesis Advance Access published on January 16, 2004
Carcinogenesis 2004 25: 841-846; doi:10.1093/carcin/bgh074 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Eilish T. Donnelly, Helen Bardwell, Geraldine Anne Thomas, E. Dillwyn Williams, Margaret Hoper, Paul Crowe, Wilson G. McCluggage, Michael Stevenson, David H. Phillips, Alan Hewer, Martin R. Osborne, and Frederick C. Campbell

Modulation of N-methyl-N-nitrosourea-induced crypt restricted metallothionein immunopositivity in mouse colon by a non-genotoxic diet-related chemical
Carcinogenesis Advance Access published on January 16, 2004
Carcinogenesis 2004 25: 847-855; doi:10.1093/carcin/bgh062 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

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