Carcinogenesis

COMMENTARY:

Stephen S. Hecht and Dietrich Hoffmann

Tobacco-specific nitrosamines, an important group of carcinogens in tobacco and tobacco smoke
Carcinogenesis 1988 9: 875-884; doi:10.1093/carcin/9.6.875 [PDF] [Request Permissions]  

ORIGINAL ARTICLES:

Marie H. Hanigan, Christopher J. Kemp, J.J. Ginsler, and Norman R. Drinkwater

Rapid growth of preneoplastic lesions in hepatocarcinogen-Sensitive C3H/HeJ male mice relative to C57BL/6J male mice
Carcinogenesis 1988 9: 885-890; doi:10.1093/carcin/9.6.885 [Abstract] [PDF] [Request Permissions]  

Svein-Ole Mikalsen, Edgar Rivedal, and Tore Sanner

Morphological transformation of Syrian hamster embryo cells induced by mineral fibres and the alleged enhancement of benzo[a]pyrene
Carcinogenesis 1988 9: 891-899; doi:10.1093/carcin/9.6.891 [Abstract] [PDF] [Request Permissions]  

Evelyne F. Lhoste, B. D. Roebuck, and Daniel S. Longnecker

Stimulation of the growth of azaserine-induced nodules in the rat pancreas by dietary camostate (FOY-305)
Carcinogenesis 1988 9: 901-906; doi:10.1093/carcin/9.6.901 [Abstract] [PDF] [Request Permissions]  

S. Vamvakas, F.J. Kordowich, W. Dekant, T. Neudecker, and D. Henschler

Mutagenicity of hexachloro-1,3-butadiene and its S-conjugates in the Ames test—role of activation by the mercapturic acid pathway in its nephrocarcinogenicity
Carcinogenesis 1988 9: 907-910; doi:10.1093/carcin/9.6.907 [Abstract] [PDF] [Request Permissions]  

Paul C. Howard, Gheorghe D. Mateescu, and Mary C. Consolo

Liver microsomal metabolism of the environmental carcinogen 3-nitrofluoranthene. I. Phenolic metabolites
Carcinogenesis 1988 9: 911-917; doi:10.1093/carcin/9.6.911 [Abstract] [PDF] [Request Permissions]  

Detlef Wölfle, Peter Münzel, Gösta Fischer, and Karl Walter Bock

Altered growth control of rat hepatocytes after treatment with 3,4,3',4'-tetrachlorobiphenylin vivo and in vitro
Carcinogenesis 1988 9: 919-924; doi:10.1093/carcin/9.6.919 [Abstract] [PDF] [Request Permissions]  

Lee-Jane W. Lu, Joachim G. Liehr, David A. Sirbasku, Erika Randerath, and Kurt Randerath

Hypomethylation of DNA in estrogen-induced and -dependent hamster kidney tumors
Carcinogenesis 1988 9: 925-929; doi:10.1093/carcin/9.6.925 [Abstract] [PDF] [Request Permissions]  

Renato Garcea, Lucia Danio, Serenella Frassetto, Patrizia Cozzolino, Maria E. Ruggiu, Maria G. Vannini, Rosa Pascale, Luciano Lenzerini, Maria M. Simile, Marco Puddu, and Francesco Feo

Reversal by ribo- and deoxyribonucleosides of dehydroepiandrosterone-induced inhibition of enzyme altered foci in the liver of rats subjected to the initiation-selection process of experimental carcinogenesis
Carcinogenesis 1988 9: 931-938; doi:10.1093/carcin/9.6.931 [Abstract] [PDF] [Request Permissions]  

Gunnar Saeter, Per E. Schwarze, Jahn M. Nesland, Niels Juul, Erik O. Pettersen, and Per O. Seglen

The polyploidizing growth pattern of normal rat liver is replaced by divisional, diploid growth in hepatocellular nodules and carcinomas
Carcinogenesis 1988 9: 939-945; doi:10.1093/carcin/9.6.939 [Abstract] [PDF] [Request Permissions]  

Noburu Ishinishi, Akiyo Tanaka, Akira Hisanaga, Takeo Inamasu, and Miyuki Hirata

Comparative study on the carcinogenicity of N-nitrosodiethylamine, N-nitrosodhnethylamine, N-nitrosomorpholine, N-nitrosopyrrolidine and N-nitrosodi-n-propylamine to the lung of Syrian golden hamsters following intermittent instillations to the trachea
Carcinogenesis 1988 9: 947-950; doi:10.1093/carcin/9.6.947 [Abstract] [PDF] [Request Permissions]  

Peter P. Fu, Robert H. Heflich, Linda S. Von Tungeln, Helena Z. Miranda, and Frederick E. Evans

Microsomal metabolism of 1-nitrobenzo[e] to a highly mutagenic K-region dihydrodiol
Carcinogenesis 1988 9: 951-958; doi:10.1093/carcin/9.6.951 [Abstract] [PDF] [Request Permissions]  

Karen L. Steinmetz, C. Kimerly Tyson, Earl F. Meierhenry, Judson W. Spalding, and Jon C. Mirsalis

Examination of genotoxicity, toxicity and morphologic alterations in hepatocytes following in vivo or in vitro exposure to methapyrilene
Carcinogenesis 1988 9: 959-963; doi:10.1093/carcin/9.6.959 [Abstract] [PDF] [Request Permissions]  

Bénédicte Saulier, Claude Prigent, Raymonde Boutelier, and Jean Claude David

Peplomycin. DNA breakage and in vitro inhibition of DNA polymerases and ligase from human normal and leukemic cells
Carcinogenesis 1988 9: 965-970; doi:10.1093/carcin/9.6.965 [Abstract] [PDF] [Request Permissions]  

Akio Matsuzawa, Tetsuya Kaneko, Akira Murakami, and Harutaka Tanaka

Enhancement of tumorigenic potential in virgin mice of a pregnancy-dependent mouse mammary tumor (TPDMT-4) by enzymatic cell dissociation
Carcinogenesis 1988 9: 971-977; doi:10.1093/carcin/9.6.971 [Abstract] [PDF] [Request Permissions]  

Tamar Kleinberger, Elhanan Sahar, and Sara Lavi

Carcinogen-mediated co-activation of two independent genes in Chinese hamster cells
Carcinogenesis 1988 9: 979-985; doi:10.1093/carcin/9.6.979 [Abstract] [PDF] [Request Permissions]  

Douglas J. Winton, Bojan Flaks, and Antonia Flaks

Quantitative electron microscopy of carcinogen-induced alterations in hepatocyte rough endoplasmic reticulum. I. Chronic effect of 3'MeDAB and short-term effects of azo dyes of different carcinogenic potentials
Carcinogenesis 1988 9: 987-999; doi:10.1093/carcin/9.6.987 [Abstract] [PDF] [Request Permissions]  

Barry Gold and Galen Brunk

The effect of pyrazole, phenobarbital, ethanol and 3-methyicholanthrene pretreatment on the in vivo and in vitro genotoxicity of N-nitrosopyrrolidine
Carcinogenesis 1988 9: 1001-1005; doi:10.1093/carcin/9.6.1001 [Abstract] [PDF] [Request Permissions]  

Terence Lawson and Donald Nagel

The production and repair of DNA damage by N-nitrosobis(2-oxopropyl)amine and azaserine in hamster and rat pancreas acinar and duct cells
Carcinogenesis 1988 9: 1007-1010; doi:10.1093/carcin/9.6.1007 [Abstract] [PDF] [Request Permissions]  

P. Hrelia, L. Murelli, M. Scotti, M. Paolini, and G. Cantelli-Forti

Organospecific activation of azathioprine in mice: role of liver metabolism in mutation induction
Carcinogenesis 1988 9: 1011-1015; doi:10.1093/carcin/9.6.1011 [Abstract] [PDF] [Request Permissions]  

L.P.A. van Houte, J.G. Westra, J. Retèl, and R. van Grondelle

A spectroscopic study of the conformation of poly d(G — C){dot}poly d(G — C) modified with the carcinogenic 2-aminofluorene
Carcinogenesis 1988 9: 1017-1027; doi:10.1093/carcin/9.6.1017 [Abstract] [PDF] [Request Permissions]  

Mary E. Schultz and R. Jack Schultz

Differences in response to a chemical carcinogen within species and clones of the livebearing fish, Poeciliopsis
Carcinogenesis 1988 9: 1029-1032; doi:10.1093/carcin/9.6.1029 [Abstract] [PDF] [Request Permissions]  

Susan Jaken and Stuart H. Yuspa

Early signals for keratinocyte differentiation: role of Ca²⁺-mediated inositol lipid metabolism in normal and neoplastic epidermal cells
Carcinogenesis 1988 9: 1033-1038; doi:10.1093/carcin/9.6.1033 [Abstract] [PDF] [Request Permissions]  

Hideki Mori, Shigeyuki Sugie, Naoki Yoshimi, Tokuro Kuniyasu, Hitoshi Iwata, Kiyoshi Kawai, and Takashi Hamasaki

Potential carcinogenicity of 5,6-dimethoxysterigmatocystin in rats
Carcinogenesis 1988 9: 1039-1042; doi:10.1093/carcin/9.6.1039 [Abstract] [PDF] [Request Permissions]  

R.J. Turesky, H.U. Aeschbacher, H.P. Würzner, P.L. Skipper, and S.R. Tannenbaum

Major routes of metabolism of the food-borne carcinogen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in the rat
Carcinogenesis 1988 9: 1043-1048; doi:10.1093/carcin/9.6.1043 [Abstract] [PDF] [Request Permissions]  

Edgar Weber, A. Moore, and Peter Bannasch

Enzyme histochemical and morphological phenotype of amphophilic foci and amphophilic/tigroid cell adenomas in rat liver after combined treatment with dehydroepiandrosterone and N-nitrosomorpholine
Carcinogenesis 1988 9: 1049-1054; doi:10.1093/carcin/9.6.1049 [Abstract] [PDF] [Request Permissions]  

Bruce P. Dunn and Richard H.C. San

HPLC enrichment of hydrophobic DNA-carcinogen adducts for enhanced sensitivity of ³²P-postlabeling analysis
Carcinogenesis 1988 9: 1055-1060; doi:10.1093/carcin/9.6.1055 [Abstract] [PDF] [Request Permissions]  

Elizabeth Snyderwine, Peter P. Roller, Richard H. Adamson, Shigeaki Sato, and Snorri S. Thorgeirsson

Reaction of N-hydroxylamine and N-acetoxy derivatives of 2-amino-3-methylimidazolo[4,5-f]quinoline with DNA. Synthesis and identification of N-(deoxyguanosin-8-yl)-IQ
Carcinogenesis 1988 9: 1061-1065; doi:10.1093/carcin/9.6.1061 [Abstract] [PDF] [Request Permissions]  

Andrew L. Rubin and Robert H. Rice

2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin and polycyclic aromatic hydrocarbons suppress retinoid-induced tissue transglutaminase in SCC-4 cultured human squamous carcinoma cells
Carcinogenesis 1988 9: 1067-1070; doi:10.1093/carcin/9.6.1067 [Abstract] [PDF] [Request Permissions]  

Lisa A. Seidman, Cynthia J. Moore, and Michael N. Gould

³²P-Postlabeling analysis of DNA adducts in human and rat mammary epithelial cells
Carcinogenesis 1988 9: 1071-1077; doi:10.1093/carcin/9.6.1071 [Abstract] [PDF] [Request Permissions]  

Ryoji Ishida and Taijo Takahashi

Increased O⁶-methylguanine-DNA methyltransferase activity and reduced mutability in 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea-resistant HeLa S3 cells
Carcinogenesis 1988 9: 1079-1083; doi:10.1093/carcin/9.6.1079 [Abstract] [PDF] [Request Permissions]  

Kazuyuki Yano, Masaru Sonoda, Yoshikatsu Sakagishi, Yasushi Sakamoto, and Keiichi Uycmura

Reactions of ultimate carcinogens with cell membranes: importance of carbamoylation of phosphatidylethanolamine by the carcinogens
Carcinogenesis 1988 9: 1085-1090; doi:10.1093/carcin/9.6.1085 [Abstract] [PDF] [Request Permissions]  

Atsuo Hattori, Heinz W. Kunz, Thomas J. Gill, III, Sylvia F. Pan, and Hisashi Shinozuka

Diversity of the promoting action of cyclosporine on the induction of murine lymphoid tumors
Carcinogenesis 1988 9: 1091-1094; doi:10.1093/carcin/9.6.1091 [Abstract] [PDF] [Request Permissions]  

SHORT COMMUNICATIONS:

Witaya Thamavit, Malcolm A. Moore, Yoshio Hiasa, and Nobuyuki Ito

Enhancement of DHPN induced hepatocellular, cholangiocellular and pancreatic carcinogenesis by Opisthorchis viverrini infestation in Syrian golden hamsters
Carcinogenesis 1988 9: 1095-1098; doi:10.1093/carcin/9.6.1095 [Abstract] [PDF] [Request Permissions]  

Laura A. Hastings, Laura L. Pashko, Marvin L. Lewbart, and Arthur G. Schwartz

Dehydroepiandrosterone and two structural analogs inhibit 12-O-tetradecanoylphorbol-13-acetate stimulation of prostaglandin E₂ content in mouse skin
Carcinogenesis 1988 9: 1099-1102; doi:10.1093/carcin/9.6.1099 [Abstract] [PDF] [Request Permissions]  

Hiroyuki Tsuda, Makoto Asamoto, Masataka Kagawa, Satoshi Uwagawa, Inoue Kazuhiko, Masahiko Inui, and Nobuyuki Ito

Positive influence of dietary deoxycholic acid on development of pre-neoplastic lesions initated by N-methyl-Nnitrosourea in rat liver
Carcinogenesis 1988 9: 1103-1105; doi:10.1093/carcin/9.6.1103 [Abstract] [PDF] [Request Permissions]  

Hans Verhagen, Bert Schutte, Michaèle M.J. Reynders, Geert H. Blijham, Foppe ten Hoor, and Jos C.S. Kleninjans

Effect of short-term dietary administration of butylated hydroxyanisole on cell kinetic parameters in rat gastro-intestinal tract, assessed by immunocytochemistry and flow cytometry
Carcinogenesis 1988 9: 1107-1109; doi:10.1093/carcin/9.6.1107 [Abstract] [PDF] [Request Permissions]  

Author index:

Author index
Carcinogenesis 1988 9: 1111; doi:10.1093/carcin/9.6.1111 [PDF] [Request Permissions]  

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